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- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
XMU-MP-1
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
2061980-01-4
纯度：>98% by HPLC,；NMR (Conforms)
分子式：C17H16N6O3S2
分子量：416.47
溶剂：DMSO (15 mg/ml)
性状：Yellow solid
存储：-20°C
Activity (short version)：Potent and selective MST1/2 kinase inhibitor
Function / Pharmacology：XMU-MP-1 is a potent, reversible, and selective inhibitor of the HIPPO pathway kinases MST1 and MST2 (IC50s = 71 nM and 38 nM respectively).1 It promoted liver repair/regeneration in mice and attenuated acetaminophen-induced liver injury. In a subarachnoid hemorrhage mouse model, XMU-MP-1 alleviated neurological deficits, brain edema, neuroinflammation, and white matter injury.2 XMU-MP-1 was also cardioprotective in mice with transverse aortic constriction3 and against ischemia/reperfusion injury4.
分子式：C17H16N6O3S2
分子量：416.47
溶剂：DMSO (15 mg/ml)
性状：Yellow solid
存储：-20°C
Activity (short version)：Potent and selective MST1/2 kinase inhibitor
Function / Pharmacology：XMU-MP-1 is a potent, reversible, and selective inhibitor of the HIPPO pathway kinases MST1 and MST2 (IC50s = 71 nM and 38 nM respectively).1 It promoted liver repair/regeneration in mice and attenuated acetaminophen-induced liver injury. In a subarachnoid hemorrhage mouse model, XMU-MP-1 alleviated neurological deficits, brain edema, neuroinflammation, and white matter injury.2 XMU-MP-1 was also cardioprotective in mice with transverse aortic constriction3 and against ischemia/reperfusion injury4.
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文献和实验该产品被引用文献
2061980-01-4
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XMU-MP-1
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