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- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
V-9302
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
1855871-76-9
纯度：98% by HPLC；NMR (Conforms)
分子式：C34H38N2O4
分子量：538.69
溶剂：DMSO (>70 mg/ml) Ethanol (>30 mg/ml)
性状：Off-white solid
存储：-20°C
Activity (short version)：Glutamine transport inhibitor
Function / Pharmacology：Selective inhibitor of the alanine-serine-cysteine transporter 2 (ASCT2 or SLC1A5; IC50 = 9.0 µM rat and 9.6 µM human).1,2 It inhibited the uptake of both glutamine and possibly other amino acids in human cancer cells and reduced in vitro viability by at least 20% in more than half of 29 cancer cell lines screened.2 V-9302 decreased mTOR activity, elevated autophagy, and increased oxidative stress in multiple animal cancer models.2-5
分子式：C34H38N2O4
分子量：538.69
溶剂：DMSO (>70 mg/ml) Ethanol (>30 mg/ml)
性状：Off-white solid
存储：-20°C
Activity (short version)：Glutamine transport inhibitor
Function / Pharmacology：Selective inhibitor of the alanine-serine-cysteine transporter 2 (ASCT2 or SLC1A5; IC50 = 9.0 µM rat and 9.6 µM human).1,2 It inhibited the uptake of both glutamine and possibly other amino acids in human cancer cells and reduced in vitro viability by at least 20% in more than half of 29 cancer cell lines screened.2 V-9302 decreased mTOR activity, elevated autophagy, and increased oxidative stress in multiple animal cancer models.2-5
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文献和实验该产品被引用文献
1855871-76-9
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文献支持
V-9302
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