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- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
GSK2636771
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
1372540-25-4
纯度：>98% by HPLC；NMR (Conforms)
分子式：C22H22F3N3O3
分子量：433.43
溶剂：DMSO (20 mg/ml)
性状：Pale yellow solid
存储：-20°C
Activity (short version)：Selective PI3Kß inhibitor
Function / Pharmacology：GSK2636771 is a potent, selective (>1000-fold over α, 10-fold over δ, and >2000-fold over γ), and orally bioavailable inhibitor of PI3Kß (IC50 = 5.2 nM).1 Active in vitro against multiple types of PTEN-deficient cancer cells. GSK2636771 potently blocked migration and invasion of DU145 prostate cancer cells.2 GSK2636771 has also been identified as a GPR39 agonist.3
分子式：C22H22F3N3O3
分子量：433.43
溶剂：DMSO (20 mg/ml)
性状：Pale yellow solid
存储：-20°C
Activity (short version)：Selective PI3Kß inhibitor
Function / Pharmacology：GSK2636771 is a potent, selective (>1000-fold over α, 10-fold over δ, and >2000-fold over γ), and orally bioavailable inhibitor of PI3Kß (IC50 = 5.2 nM).1 Active in vitro against multiple types of PTEN-deficient cancer cells. GSK2636771 potently blocked migration and invasion of DU145 prostate cancer cells.2 GSK2636771 has also been identified as a GPR39 agonist.3
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文献和实验该产品被引用文献
1372540-25-4
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GSK2636771
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