- 询价
- WYTSCI
- 进口
- WT-AY-B11451
- 2025年07月09日
2 年钻石会员
企业认证
相关产品推荐更多 >
![1,1'-[Oxybis(methylene-4,1-phenyleneoxy)]bis[3-[(1-methylethyl)amino]-2-propanol Fumarate-d14 (Bisoprolol Fumarate Impurity)](https://img1.dxycdn.com/p/s14/2025/0412/559/0848855653632190191.jpg!wh200)
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
TASIN-1
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
1678515-13-3
纯度：98% by HPLC；NMR (Conforms)
分子式：C18H28N2O3S·HCl
分子量：388.95
溶剂：DMSO (20 mg/ml)
性状：White or off-white solid
存储：-20°C
Activity (short version)：Selectively induces apoptosis in cells with APC truncations
Function / Pharmacology：Selectively induces apoptosis in cells with truncations in the adenomatous polyposis coli (APC) gene (but not normal cells or wild type cancer cells), an important multifunctional tumor suppressor gene.1 IC50 = 70nM for DLD1 cell line. It inhibited cancer cell growth in human tumor xenografts (DLD1 and HT29 tumors) and a genetically engineered mouse model (CPC;Apc) of colorectal cancer. TASIN-1 induces ER stress-dependent JNK activation with ROS production and AKT inhibition via cholesterol depletion.2
分子式：C18H28N2O3S·HCl
分子量：388.95
溶剂：DMSO (20 mg/ml)
性状：White or off-white solid
存储：-20°C
Activity (short version)：Selectively induces apoptosis in cells with APC truncations
Function / Pharmacology：Selectively induces apoptosis in cells with truncations in the adenomatous polyposis coli (APC) gene (but not normal cells or wild type cancer cells), an important multifunctional tumor suppressor gene.1 IC50 = 70nM for DLD1 cell line. It inhibited cancer cell growth in human tumor xenografts (DLD1 and HT29 tumors) and a genetically engineered mouse model (CPC;Apc) of colorectal cancer. TASIN-1 induces ER stress-dependent JNK activation with ROS production and AKT inhibition via cholesterol depletion.2
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
1678515-13-3
技术资料暂无技术资料 索取技术资料
文献支持
TASIN-1
询价
