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![1,1,1-Trifluoromethanesulfonic Acid (E)-4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl Ester](https://img1.dxycdn.com/p/s14/2025/0412/500/2156140662334090191.jpg!wh200)
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- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
NH125
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
278603-08-0
分子式：C27H45IN2
分子量：524.56
溶剂：DMSO (>25 mg/ml) Ethanol (>25 mg/ml)
性状：Off-white solid
存储：-20°C
Activity (short version)：Eukaryotic elongation factor 2 (eEF-2) kinase inhibitor
Function / Pharmacology：NH125 was originally discovered as an antibacterial agent active against various Gram-positive and -negative bacteria via inhibition of histidine protein kinase.1 It was also found to be a potent inhibitor of eukaryotic elongation factor 2 (eEF-2) kinase (IC50 = 60 nM) with efficacy against a broad spectrum of human cancer cell lines.2 Other studies have linked the anticancer effects of NH125 to induction of eEF2 phosphorylation.3,4 NH125 has also been shown to engage the EIF2a-ATF4-CHOP axis resulting in induction of DR5 expression.5 Treatment of glioma stem cells with NH125 resulted in a sustained decrease in tumor volume via activation of integrated stress response (ISR) and GADD45 pathways.5
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文献和实验人 糖类抗原 125(CA125) 酶联免疫分析（ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中 糖类抗原 125(CA125) 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中人 糖类抗原 125(CA125) 水平。用纯化的人 糖类抗原 125(CA125) 抗体包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 糖类抗原 125(CA125
NH4AcandEtOHprecipitationofDNA
Add NH4 Ac (10 M stock or solid) to the sample for a final concentration of 2.5 M, mix (spin at 4℃, transfer the supernatant to a new tube; optional spin for extra purification of the DNA), add 2.5 volumes of EtOH
NH4Ac and EtOH precipitation of DNA
NH4 Ac and EtOH precipitation of DNA Add NH4 Ac (10M stock or solid) to the sample
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