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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
Leu-Leu-OMe HBr
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
16689-14-8
纯度：98% by HPLC；NMR (Conforms)
分子式：C13H26N2O3 HBr
分子量：339.27
溶剂：DMSO (35 mg/ml) Water (40 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：Lysosomal damaging agent
Function / Pharmacology：Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4
分子式：C13H26N2O3 HBr
分子量：339.27
溶剂：DMSO (35 mg/ml) Water (40 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：Lysosomal damaging agent
Function / Pharmacology：Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4
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文献和实验该产品被引用文献
16689-14-8
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Leu-Leu-OMe HBr
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