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- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
Leu-Leu-OMe HBr
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
16689-14-8
分子式：C13H26N2O3 HBr
分子量：339.27
溶剂：DMSO (35 mg/ml) Water (40 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：Lysosomal damaging agent
Function / Pharmacology：Leu-Leu-OMe is a lysosomal damaging agent (lysosomotropic). It is condensed into a membranolytic polymer via the transpeptidase action of cathepsin C within lysosomes.1,2 May be used to induce a lysosomal damage model in cells.3,4 LLOMe-induced lysosomal damage elicits ubiquitin puncta formation on lysosomes1. Induces apoptosis in human mast cells via lysosome destabilization leaving fibroblasts and HEK-293 cells largely resistant5. Induces lysophagy.4
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文献和实验TR Tn3 terminal inverted repeats lacZ 5'-truncated lacZ gene encoding beta-galactosidase LEU2 LEU2 gene from S. cerevisiae amp Encodes beta-lactamase loxP lox site, target for Cre
Synthesis of Cyclopropane-Containing Leu-Enkephalin Analogs
of this chapter is to describe the preparation of a novel cyclopropane-containing cis -substituted (-Glyψ[CHOH-cp-CONH]-) subunit, which replaces Gly 2 -Gly 3 subunit of the Leu-enkephalin (Tyr-Gly-Gly-Phe-Leu) framework shown in Fig. 1 . Fig
Methods for use with the mTn-lacZ/LEU2-mutagenized library
. It is then transformed into a leu2 strain of yeast. This procedure is outlined in this figure . Use of a circle-zero strain will prevent recovery of insertions in the 2-micron plasmid. The best strategy is to screen a few thousand transformants from each pool
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