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- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
HC-258
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
Unknown
纯度：>98% by TLC,；NMR (Conforms)
分子式：C20H24N2O2
分子量：324.42
溶剂：DMSO (>25 mg/ml)
性状：Yellow oil
存储：-20°C
Activity (short version)：Covalent TEAD inhibitor
Function / Pharmacology：HC-258 is a covalent inhibitor of TEAD (transcriptional enhanced associate domain), an important component of the Hippo pathway. It was able to reduce gene expression levels of CTGF, CYR61, AXL, and NF2 in MDA-MB-231 breast cancer cells. HC-258 also reduced MDA-MB-231 cell migration.
分子式：C20H24N2O2
分子量：324.42
溶剂：DMSO (>25 mg/ml)
性状：Yellow oil
存储：-20°C
Activity (short version)：Covalent TEAD inhibitor
Function / Pharmacology：HC-258 is a covalent inhibitor of TEAD (transcriptional enhanced associate domain), an important component of the Hippo pathway. It was able to reduce gene expression levels of CTGF, CYR61, AXL, and NF2 in MDA-MB-231 breast cancer cells. HC-258 also reduced MDA-MB-231 cell migration.
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文献和实验该产品被引用文献
Unknown
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文献支持
HC-258
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