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- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
GW-501516
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
317318-70-0
纯度：98% by TLC；NMR (Conforms)
分子式：C21H18F3NO3S2
分子量：453.50
溶剂：DMSO (40 mg/ml) Ethanol (20 mg/ml)
性状：Off-white solid
存储：-20°C
Activity (short version)：PPARδ agonist
Function / Pharmacology：Potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance.2 Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation.3 Upregulates human Sirt1 via Sp1 activation.4 Along with exercise, GW-501516 synergistically increases running endurance.5
分子式：C21H18F3NO3S2
分子量：453.50
溶剂：DMSO (40 mg/ml) Ethanol (20 mg/ml)
性状：Off-white solid
存储：-20°C
Activity (short version)：PPARδ agonist
Function / Pharmacology：Potent and selective PPARδ (NR1C2) agonist, EC50=1.2 nM and 1000-fold selective over other PPAR subtypes.1 Induces apolipoprotein A1-mediated cholesterol efflux in vitro.1 Improves hematopoietic stem cell maintenance.2 Prevents downregulation of AMPK caused by a high-fat diet in liver and increases fatty acid oxidation.3 Upregulates human Sirt1 via Sp1 activation.4 Along with exercise, GW-501516 synergistically increases running endurance.5
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文献和实验该产品被引用文献
317318-70-0
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GW-501516
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