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- 文献和实验
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- 保存条件:
RT
- 保质期:
咨询
- 英文名:
HTS01037
- 库存:
1000+
- 供应商:
上海维亦特生物
- CAS号:
682741-29-3
纯度:98% by HPLC,;NMR (Conforms)
分子式:C14H11NO5S2
分子量:337.37
溶剂:DMSO (50 mg/ml)
性状:Yellow solid
存储:RT
Activity (short version):FABP inhibitor
Function / Pharmacology:Inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cultured macrophages. Acts as an antagonist of the protein-protein interaction between AFABP/aP2 and hormone sensitive lipase but does not activate PPARγ in macrophages1. Inhibits FABP-dependent and fatty acid-stimulated leukotriene C4 biosynthesis2. Reduces intracellular free fatty acid levels, lowering macrophage inflammation and ER stress3. Reduces LPS-stimulated IL-1β secretion in a mouse model4. Inhibits VLDL-induced foam cell formation5.
分子式:C14H11NO5S2
分子量:337.37
溶剂:DMSO (50 mg/ml)
性状:Yellow solid
存储:RT
Activity (short version):FABP inhibitor
Function / Pharmacology:Inhibits fatty acid binding proteins. Inhibits lipolysis in 3T3-L1 adipocytes and reduces LPS-stimulated inflammation in cultured macrophages. Acts as an antagonist of the protein-protein interaction between AFABP/aP2 and hormone sensitive lipase but does not activate PPARγ in macrophages1. Inhibits FABP-dependent and fatty acid-stimulated leukotriene C4 biosynthesis2. Reduces intracellular free fatty acid levels, lowering macrophage inflammation and ER stress3. Reduces LPS-stimulated IL-1β secretion in a mouse model4. Inhibits VLDL-induced foam cell formation5.
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文献和实验该产品被引用文献
682741-29-3
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HTS01037
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