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- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
Stavudine
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
3056-17-5
纯度：>98% by HPLC,；NMR (Conforms)
分子式：C10H12N2O4
分子量：224.22
溶剂：DMSO (20 mg/ml) Water (20 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：HIV reverse transcriptase inhibitor
Function / Pharmacology：Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs).1,2 Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition.3 Reduces production of IL-18 and caspase-1 and stimulates Aβ-induced autophagy in macrophages.4
分子式：C10H12N2O4
分子量：224.22
溶剂：DMSO (20 mg/ml) Water (20 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：HIV reverse transcriptase inhibitor
Function / Pharmacology：Thymidine derivative that acts as an HIV nucleoside reverse transcriptase inhibitor (NRTI) (EC50 = 8.8 nM for HIV-1 replication in human PBMCs).1,2 Down-modulates P2X7-mediated NLRP3 inflammasome activation independent of reverse transcriptase inhibition.3 Reduces production of IL-18 and caspase-1 and stimulates Aβ-induced autophagy in macrophages.4
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文献和实验该产品被引用文献
3056-17-5
相关实验
Line Probe Assay for Detecting Mutations in HIV-1 Reverse Transcriptase
is error-prone, and the infection is characterized by its quasi-species nature. Antiretroviral treatment with such compounds as zidovudine (AZT), zalcitabine (ddC), didanosine (ddI), stavudine (d4T), and lamivudine (3TC) select for quasispecies variants
素 staurosporin|星形孢菌素[来自链霉菌的蛋白激酶C抑制剂] stavudine|【商】双脱氧胸苷 steapsase|胰脂肪酶 steapsin|胰脂肪酶 steel factor|青灰因子[癌基因产物c-kit的配体，最初发现与小鼠的青灰色表型有关] stele|中柱 stem cell|干细胞 stemonine|百部碱
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