4-fluoro-1-[tris(propan-2-yl)s

Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O6‐Ethers via Intermediate O6‐(Benzotriazol‐1‐yl) Derivatives

for the etherification at the O 6 ?position of silyl?protected inosine, guanosine, and 2??deoxyguanosine is described. Typically, a THF solution of the silylated nucleoside is treated with 1H ?benzotriazol?1?yloxy?tris(dimethylamino)phosphonium hexafluorophosphate (BOP

Synthesis and Properties of 7‐Substituted 7‐Deazapurine (Pyrrolo[2,3‐d]pyrimidine) 2′‐Deoxyribonucleosides

Materials 2‐Amino‐4‐chloro‐7H ‐pyrrolo[2,3‐d ]pyrimidine ( S.17 ; see Seela et al., ) Anhydrous pyridine

Biotinylation of a Propargylated Cyclic (3′‐5′) Diguanylic Acid and of Its Mono‐6‐Thioated Analog Under “Click” Conditions

12 from the biotinylated azide 11 . Abbreviations: TBTA, tris ‐(benzyltriazolylmethyl)amine; Gua, guanin‐9‐yl. Adapted with permission from Grajkowski et al. (). Copyright 2010 American Chemical Society.