Recombinant human PDGF-AA

| 产品信息

品名:NebuSelect™ Recombinant human PDGF-AA

货号:NBL-243155

品牌:Nebulabio

规格:100ug；500ug；1mg

 

| 产品描述

NebuSelect™ Recombinant human PDGF-AA, His-tag(Cat#NBL-243155) is expressed in E.coli.

 

| 产品属性

别名:Platelet-derived growth factor subunit A;PDGF subunit A;PDGF-1;Platelet-derived growth factor A chain;Platelet-derived growth factor alpha polypeptide; PDGFA;PDGF1

物种:Human

表达系统:E.coli

分子量:The protein has a predicted MW of 14.1kDa. 

靶点名称:PDGF-AA

Accession:P04085

纯度: ＞90%

形式:Powder

Endotoxin:＜1EU/ug(LAL Method)

储存条件：4°C for short term. ；-20°C for long term.

 

| 靶点信息

Tumor necrosis factor ligand superfamily member 13 (TNFSF13) also known as a proliferation-inducing ligand (APRIL) is a member PDGF (Platelet-derived growth factor) is one among numerous growth factors that regulate cell growth and division. The PDGF family forms five dimeric ligands, PDGF-AA, PDGF-BB, PDGF-CC, PDGF-DD, and PDGF-AB, which activate cognate receptor tyrosine kinases PDGFR-α and PDGFR-β. Upon binding to its tyrosine kinase receptor PDGF-αα, PDGF-AA stimulates the proliferation of osteoblastic cells and may exert autocrine and paracrine effects in regulating bone-forming processes. PDGF-AA is the most well characterized mitogen that is not restricted to any kind of tumor cell type but was seen in osteoblastic cells as well as in pleomorphic tumor elements.

 

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