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- 询价记录
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- 库存：
咨询
- 英文名：
Lipopolysaccharides
- CAS号：
咨询
- 保质期：
Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
- 供应商：
北京索莱宝科技有限公司
- 保存条件：
Powder:2-8℃，2 years;Insolvent(母液):-20℃，6 months;-80℃，1 year
- 规格：
10mg /20mg/ 50mg / 100mg/200mg/5mg
| 规格： | 10mg | 产品价格： | ￥580.0 |
|---|---|---|---|
| 规格： | 20mg | 产品价格： | ￥1040.0 |
| 规格： | 50mg | 产品价格： | ￥2300.0 |
| 规格： | 100mg | 产品价格： | ￥4480.0 |
| 规格： | 200mg | 产品价格： | ￥8800.0 |
| 规格： | 5mg | 产品价格： | ￥440.0 |
本品来源于Escherichia coli 055:B5。
纯度：<3% Protein (purified by phenol extraction)
可用于诱导细胞或者诱导疾病研究的动物模型如炎症反应等相关实验。
Lipopolysaccharides (LPS) 脂多糖是革兰氏阴性细菌细胞壁中的一种特有成分，位于细胞壁的最外层并暴露于非荚膜细菌的细胞表面，有利于维持细胞外膜的完整性，保护细菌免受胆汁盐和脂类抗生素的破坏。结构上，脂多糖由类脂A、核心多糖和O-多糖侧链组成。其中类脂质A是构成细菌内毒素的主要成分，决定其毒性强弱；而O-多糖侧链在不同细菌间是高度变化的，特异性决定细菌的血清型。LPS可以引起免疫刺激的级联反应和机体的毒性病理生理活动.
使用本产品的应用案例（仅供参考）
| 应用 | 样本 | 处理条件 | 数据来源文 |
| In Vitro | RAW264.7 cells | 100 ng/mL LPS，24 h at 37 ℃ | doi: 10.1021/acsami.2c23323. Epub 2023 Apr 12. PMID: 37042619. |
| In Vitro | RAW264.7 cells | 1 μg/mL of LPS，48h | doi: 10.1016/j.bioactmat.2020.08.024. PMID: 32995674;PMCID: PMC7493086. |
| In Vitro | RAW264.7 cells | 1 μg/mL of LPS，24h | doi: 10.1021/acs.jafc.0c03732. Epub 2020 Aug 18. PMID: 32786864. |
| In Vitro | RAW264.7 cells | 0.5 μg/mL of LPS，24h | doi: 10.18388/abp.2020_5190. PMID: 32421285. |
| In Vitro | RAW276.4 | 500 ng/mL Lipopolysaccharide/LPS；1 h | doi: 10.1016/j.bioactmat.2023.04.011. PMID: 37180642; |
| In Vitro | HepG2 cells | 1 μg/mL LPS，12h | doi: 10.1016/j.talanta.2020.120926. Epub 2020 Mar 14. PMID: 32456892. |
| In Vitro | B淋巴细胞 | 1µg/ml LPS | doi: 10.1016/j.ejphar.2020.173673. Epub 2020 Oct 22. PMID: 33098836. |
| In Vitro | 淋巴细胞 | 15 µg/mL LPS | doi: 10.1080/13880209.2019.1699123. PMID: 31847682;PMCID: PMC6968662. |
| In Vitro | RAW264.7 cells | 100 ng ml−1，12 h | doi: 10.1039/d3fo03685e. PMID: 37975193. |
| In Vitro | Raw264.7 cells | 2 h | doi: 10.2147/IJN.S502850. PMID: 40007906;PMCID: PMC11853999. |
| In Vitro | 人脐静脉内皮细胞（HUVEC） | 24 h | doi: 10.2147/IJN.S502850. PMID: 40007906;PMCID: PMC11853999. |
| In Vitro | HK-2 cells | 10 μg/ml LPS，12h | doi: 10.5114/ceji.2024.145730. Epub 2024 Dec 11. PMID: 39944255;PMCID: PMC11811718. |
| In Vitro |
THP-1 macrophages |
5×105/well，100 ng/mL |
doi: 10.1016/j.bioactmat.2024.08.016. PMID: 39280578;PMCID: PMC11399477. |
| In Vivo | Mice | The LPS-induced acute lung inflammation model | doi: 10.1016/j.ejps.2020.105290. Epub 2020 Mar 2. PMID: 32135270. |
| In Vivo | Female wild-type C57BL/6 mice | 2 mg/kg/every 3 days LPS, i.p | doi: 10.1136/gutjnl-2020-320777. Epub ahead of print. PMID: 33122176;PMCID: PMC8292576. |
| In Vivo | Tg (Lyz:DsRed) transgenic line斑马鱼幼虫 | doi: 10.1016/j.chemosphere.2020.127849. Epub 2020 Aug 22. PMID: 33297003. | |
|
In Vitro |
L929 cells | 20 μg/mL LPS for 2 h |
doi: 10.1002/smll.202507586. Epub 2025 Aug 13. PMID: 40801489. |
| In Vitro | RAW264.7 | 100 ng/ mL LPS for 24 h |
doi: 10.1002/smll.202507586. Epub 2025 Aug 13. PMID: 40801489. |
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|
AuthorXiaojuan Jiang, Yihua Lin, Yunlong Wu, Caixia Yuan, Xuli Lang, Jiayun Chen, Chunyan Zhu, Xinyi Yang, Yu Huang, Hao Wang, Caisheng Wu |
Publish_toJournal of Pharmaceutical Analysis |
|
IF14.0260 |
PMID36605579 |
Inosine: A broad-spectrum anti-inflammatory against SARS-CoV-2 infection-induced acute lung injury via suppressing TBK1 phosphorylation
|
AuthorNingning Wang, Entao Li, Huifang Deng, Lanxin Yue, Lei Zhou, Rina Su, Baokun He, Chengcai Lai, Gaofu Li, Yuwei Gao, Wei Zhou, Yue Gao |
Publish_toJournal of Pharmaceutical Analysis |
|
IF14.0260 |
PMID36313960 |
Cleaved SPP1-rich extracellular vesicles from osteoclasts promote bone regeneration via TGFβ1/SMAD3 signaling
|
AuthorAbdullah Faqeer, Mengzhen Wang, Gulzar Alam, Arshad Ahmed Padhiar, Dexiu Zheng, Zhiming Luo, Irene Shuping Zhao, Guangqian Zhou, Jeroen J.J.P. van den Beucken, Huanan Wang, Yang Zhang |
Publish_toBIOMATERIALS |
|
IF14.0000 |
PMID38465579 |
Polystyrene microplastics promote liver inflammation by inducing the formation of macrophages extracellular traps
|
AuthorKai Yin, Dongxu Wang, Yue Zhang, Hongmin Lu, Lulu Hou, Tiantian Guo, Hongjing Zhao, Mingwei Xing |
Publish_toJOURNAL OF HAZARDOUS MATERIALS |
|
IF13.6000 |
PMID36958159 |
Vitamin C encapsulated biomimetic nanogels with macrophage membrane decoration for chronic wound healing
|
AuthorXin Yang, Xiang Lin, Jinbo Li, Tapani Viitala, Yuanjin Zhao, Hongbo Zhang, Luoran Shang |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.3000 |
PMID |
In situ reprogramming of fibroblasts into antigen-presenting pseudo-dendritic cells via IFN-β-engineered protoplast-derived exosomes delivered by microneedle arrays to enhance adaptive immunity
|
AuthorYue Yin, Shijie Zhao, Wei Li, Yuan Cui, Thanh Loc Nguyen, Ge Gao |
Publish_toTheranostics |
|
IF13.3000 |
PMID40963909 |
MXene-Decorated Nanofibrous Membrane with Programmed Antibacterial and Anti-Inflammatory Effects via Steering NF-百B Pathway for Infectious Cutaneous Regeneration
|
AuthorYixuan Huang, Shuai He, Sheng Yu, Hannah M. Johnson, Yau Kei Chan, Zheng Jiao, Shouteng Wang, Zixiang Wu, Yi Deng |
Publish_toSmall |
|
IF13.3000 |
PMID37759420 |
Glutathione-responsive nanoplatforms trigger gaseous intervention of intestinal inflammation through TLR4/MD2/MyD88/NF-κB/iNOS pathway activation and gut microbiota modulation
|
AuthorYanfei Li, Beiwei Zhu, Tao Chen, Lihang Chen, Di Wu, Xinchuang Wang, Dongmei Li, Wei Li, Yinshi Sun, Jiangning Hu |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.3000 |
PMID |
Microgels-Encapsulated Magnesium/Emodin-based metal organic framework nanorods for diabetic bone regeneration
|
AuthorDi Wang, Yajie Wang, Daiying Song, Baoshuai Bai, Zheng Ci, Yan Gong, Yujie Hua, Xiansong Wang, Guangdong Zhou |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.3000 |
PMID |
Bioinspired micro-nano hierarchical delivery system for sequential targeted therapy of inflammatory bowel disease
|
AuthorPeipei Xi, Xiangyu Wei, Yongxin Xu, Nengjie Yang, Yunan Wang, Yuting Huang, Minjie Chen, Ya Wen, Yujuan Zhu, Yuanjin Zhao, Zhifeng Gu |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.3000 |
PMID |
Immunomodulatory melanin@Pt nanoparticle-reinforced adhesive hydrogels for healing diabetic oral ulcers
|
AuthorErya Cai, Xiaoliang Qi, Yizuo Shi, Xinxin Ge, Yajing Xiang, Hangbin Xu, Ying Li, Yulong Lan, Jianliang Shen, Rongdang Hu, Hui Deng |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.3000 |
PMID |
Milk-derived exosome as delivery system for lutein encapsulation in alleviating dry eye disease
|
AuthorShida Wu, Wentao Su, Kuiyou Wang, Hongliang Li, Shasha Huang, Shanshan Tie, Mingqian Tan |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.3000 |
PMID |
Programming of macrophage polarization in different stages for accelerating wound healing
|
AuthorMeng Zhu, Jinzhao Ou, Yuzhou Chen, Ye Tian, Wei Song, Xiaohua Hu, Xiaoyan Ju, Shidong Jiang, Sha Huang, Zhongwei Niu |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.3000 |
PMID |
Enhanced Mitochondrial Targeting and Inhibition of Pyroptosis with Multifunctional Metallopolyphenol Nanoparticles in Intervertebral Disc Degeneration
|
AuthorHao Zhou, Qiuping Qian, Qizhu Chen, Tao Chen, Chenyu Wu, Linjie Chen, Zhiguang Zhang, Ouqiang Wu, Yuxin Jin, Xinzhou Wang, Zhenyu Guo, Jing Sun, Jun Zhang, Shuying Shen, Xiangyang Wang, Morgan Jones, Moonis Ali Khan, Pooyan Makvandi, Yunlong Zhou, Aimin W |
Publish_toSmall |
|
IF13.3000 |
PMID37953455 |
Injectable natural hydrogel with spatiotemporal self-strengthening, antibacterial and anti-inflammatory properties for treating diabetic wound
|
AuthorYucong Gu, Shihua Mao, Wenli Yu, Tingben Huang, Jintao Yang |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.3000 |
PMID |
Constructing a highly efficient CuS/Cu9S5 heterojunction with boosted interfacial charge transfer for near-infrared photocatalytic disinfection
|
AuthorZe Zhang, Jingyu Sun, Shudi Mo, Jongguk Kim, Donggang Guo, Jing Ju, Qilin Yu, Mingyang Liu |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2730 |
PMID |
Platinum-cerium bimetallic nano-raspberry for atherosclerosis treatment via synergistic foam cell inhibition and P2Y12 targeted antiplatelet aggregation
|
AuthorSiyu Wang, Yue Zhou, Xiaoyang Liang, Min Xu, Nan Li, Kang Zhao |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2730 |
PMID |
Bi2O2Se nanosheets coated with rosmarinic acid for colon-targeted treatment of inflammatory bowel disease
|
AuthorJiahu Yao, Yang Yang, Hu Zhao, Chuanming Wang, Liang Jin, Tengyun Long, Wei Huang, Xiang Zhan, Xin Li, Xin Chen, Jinhu Xie, Bin Wu, Chuansi Wang, Liling Huang, Hongnian Pan, Xuan Nie, Changjun Yu, Wei Chen |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
TfR-aptamer programmed DNA nanoflowers penetrate the blood-brain barrier for synergistic NLRP3 silencing and neuroinflammation therapy
|
AuthorXiangji Kong, Biao Hu, Xinwei Luo, Jie Zhou, Chi Zhang, Ruiyang Zi, Chao Zhang, Yuying Zhang, Haoran Jiang, Taorui Liu, Yan Zhang, Yan Dong, Xiang Zhao, Jun Hu |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
Endocrine-driven FGF21 mRNA therapy via route-adaptable lipopolymer nanoparticles for the treatment of pancreatitis
|
AuthorJia Liu, Ling Zeng, Qian Shen, Tingfeng Yu, Yupeng Ren, Xinxiu Cao, Lingyun Wang, Jinjin Chen |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
A versatile hydrogel with sequential drug-releasing capability for the programmable healing of suppurative otitis media
|
AuthorDatao Hu, Jinpeng Wen, Hanchao Zhou, Yunhe Zheng, Jiangchuan He, Yu Huang, Ting Wang, Kailai Liu, Yuchen Zhang, Jingya Qu, Pengchong Wang, Ke Wang |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
Orally administered metal–organic framework nanocubes for sequence-targeted quercetin delivery in colitis alleviation
|
AuthorRunan Zhao, Tao Chen, Shumeng Hu, Xuesong Chi, Songfeng Yu, Yanfei Li, Wenjun Wang, Beiwei Zhu, Donghong Liu, Jiangning Hu |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
A Sierpiński-fractal supermolecule constructed lipid chemiluminescent nanosensor for mapping inflammatory status in murine models
|
AuthorJiming Wei, Yaqi Wang, Boyuan Wang, Rongmei Ma, Qian Qiao, Jiagen Lv, Tuanrui Dong, Jitong Lyu |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
Self-assembling metal–polyphenol–protein nanocomplex enhancing islet graft survival and transplantation outcome
|
AuthorZeqing Wang, Yixuan Zhu, Huixiang Sheng, Yang Cheng, Ying Zhang, Yifei Yang, Zhuoxun Huang, Xiaoyue Chen, Yifan Qiu, Rui Wu, Di Huang, Wenjing Gong, Longfa Kou, Qing Yao |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
Emulsion coating: One-pot method preparing the sealable microporous surfaces with antibacterial and antithrombotic properties
|
AuthorJingze Liu, Yueze Hong, Yao Xiong, Yage Hu, Jiaqi Wang, Yuan Wei, Tong Wang, Haichao Yu, Ruipeng Xue, Li Yang, Gaocan Li, Rifang Luo, Fanjun Zhang, Yunbing Wang |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
Bimetallic ion crosslinked hydrogels sequentially releasing immunomodulatory factors and osteogenic factors to promote bone integration of 3D printed titanium alloy prostheses
|
AuthorXiao Sheng, Zhenjia Che, Chuncheng Shen, Jingtao Wu, Chenhao Qiu, Chenjie Tan, Junjie Mao, Bo Li, Hang Yu, Jianyou Li, Wei Liu, Chen Li, Xiongfeng Li, Hongliang Gao |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
Macrophage-targeted, ROS-removing and H2S-releasing nanomicelle encapsulated in hydrogel microspheres for the treatment of osteoarthritis
|
AuthorJun Tao, Hui Deng, Zhengnan Li, Liping Cao, Yanfei Rao, Zhanhai Yin |
Publish_toCHEMICAL ENGINEERING JOURNAL |
|
IF13.2000 |
PMID |
EGCG modified small intestine submucosa promotes wound healing through immunomodulation
|
AuthorRong Nie, Qing-Yi Zhang, Jie Tan, Zi-Yuan Feng, Kai Huang, Ning Sheng, Yan-Lin Jiang, Yu-Ting Song, Chen-Yu Zou, Long-Mei Zhao, He-Xi Li, Rui Wang, Xing-Li Zhou, Juan-Juan Hu, Chen-Yu Wu, Jesse Li-Ling, Hui-Qi Xie |
Publish_toCOMPOSITES PART B-ENGINEERING |
|
IF13.1000 |
PMID |
Time-Dependent Electrical Active and Ultrasound-Responsive Calcium Titanate Implant Coating with Immunomodulation, Osteogenesis, and Customized Antibacterial Activity
|
AuthorXianglin Dai, Tianze Li, Peng Wei, Yingying Xu, Chenxinyan Jiang, Xuyue Zhang, Xianhua Zhang, Lan Liao, Xiaolei Wang |
Publish_toSmall |
|
IF13.0000 |
PMID39428890 |
Hydrogel Strain Sensors for Integrating Into Dynamic Organ-on-a-Chip
|
AuthorWenqi She, Chong Shen, Zaifei Xue, Bin Zhang, Guoliang Zhang, Qin Meng |
Publish_toSmall |
|
IF13.0000 |
PMID39846814 |
Coordination-Driven Nanomedicine Mitigates One-Lung Ventilation-Induced Lung Injury via Radicals Scavenging and Cell Pyroptosis Inhibition
|
AuthorYujie Fan, Yangqin Ou, Ting Xiao, Ziye Wei, LiLing Zhu, Chenghao Zhu, Yiran Ma, Shuangquan Qu, Wenhu Zhou |
Publish_toSmall |
|
IF13.0000 |
PMID39115137 |
Polyphenol-Scaffolded Modular Assembly of Heterotypic Cell–Cell Assemblies for Potentiating Cancer Immunotherapy
|
AuthorGuidong Gong, Qimin Yin, Qinling Liu, Yajing Zhang, Jinyuan Liu, Mengyuan Dai, Jiawen Li, Xianglian He, Jiezhou Pan, Yunxiang He, Bo Wang, Jiyu Tong, Junling Guo |
Publish_toSmall |
|
IF13.0000 |
PMID39610194 |
In Situ Proefferocytosis Microspheres as Macrophage Polarity Converters Accelerate Osteoarthritis Treatment
|
AuthorYong Wang, Chaoyu Pu, Zeyu Han, Yawei Du, Liang Chen, Yanran Huang, Yue Luo, Chao Xiang, Jiangtao He, Lu Chen, Wenguo Cui, Ke Jiang, Yuling Li |
Publish_toSmall |
|
IF13.0000 |
PMID39780612 |
LncRNA IFITM4P promotes immune escape by up-regulating PD-L1 via dual mechanism in oral carcinogenesis
|
AuthorLinjun Shi, Yuquan Yang, Mengying Li, Chenxi Li, Zengtong Zhou, Guoyao Tang, Lan Wu, Yilin Yao, Xuemin Shen, Zhaoyuan Hou, Hao Jia |
Publish_toMOLECULAR THERAPY |
|
IF12.9100 |
PMID35051616 |
A microsphere-vesicle hybrid system for tumor treatment through enhancement of innate and adaptive immune responses
|
AuthorYida Chen, Xinyi Cheng, Can Zhu, Mimi Chen, Yi Wang, Chang Liu, Jie Sun, Hao Shen, Junjie Niu, Huilin Yang, Xingzhi Liu, Wenguo Cui, Qin Shi |
Publish_toBIOMATERIALS |
|
IF12.9000 |
PMID |
Local delivery of stem cell spheroids with protein/polyphenol self-assembling armor to improve myocardial infarction treatment via immunoprotection and immunoregulation
|
AuthorChuanfeng An, Fei Shao, Canling Long, Yujie Zhang, Wen Nie, Rui Zeng, Zhenzhen Dou, Yuan Zhao, Yuanyuan Lin, Shiying Zhang, Lijun Zhang, Changle Ren, Yang Zhang, Guangqian Zhou, Huanan Wang, Jia Liu |
Publish_toBIOMATERIALS |
|
IF12.8000 |
PMID38513434 |
Material-driven immunomodulation and ECM remodeling reverse pulmonary fibrosis by local delivery of stem cell-laden microcapsules
|
AuthorYujie Zhang, Yuan Zhao, Chuanfeng An, Yiyang Guo, Yubin Ma, Fei Shao, Yonggang Zhang, Kai Sun, Fang Cheng, Changle Ren, Lijun Zhang, Bingbing Sun, Yang Zhang, Huanan Wang |
Publish_toBIOMATERIALS |
|
IF12.8000 |
PMID39178558 |
Anti-pyroptosis biomimetic nanoplatform loading puerarin for myocardial infarction repair: From drug discovery to drug delivery
|
AuthorKun Wang, Yu Sun, Ke Zhu, Yiqiong Liu, Xiao Zheng, Zichen Yang, Fulong Man, Li Huang, Ziyang Zhu, Qi Huang, Yan Li, Haiqing Dong, Jun Zhao, Yongyong Li |
Publish_toBIOMATERIALS |
|
IF12.8000 |
PMID39427429 |
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis
|
AuthorYangY;LiL;XuC;WangY;WangZ;ChenM;JiangZ;PanJ;YangC; |
Publish_toGut |
|
IF12.7780 |
PMID33122176 |
Natural fish swim bladder-derived MPN-nanofibrous biomimetic system exhibit ECM-responsive signal regulation and promote robust tendon–bone healing
|
AuthorShi Lei, Zhou Peng, Ye Cong, Sun Jie, Ma Hongdong, Tao Ran, Zhang Peng, Han Fei |
Publish_toJOURNAL OF NANOBIOTECHNOLOGY |
|
IF12.6000 |
PMID |
Gasotransmitter nitric oxide imaging in Alzheimer's disease and glioblastoma with diamino-cyclic-metalloiridium phosphorescence probes
|
AuthorHaitao Ding, Li Luo, Liping Su, Junyang Chen, Yunkun Li, Lei Hu, Kui Luo, Xiaohe Tian |
Publish_toBIOSENSORS & BIOELECTRONICS |
|
IF12.6000 |
PMID38145594 |
A nanocomposite xanthan gum/puerarin supramolecular hydrogel with immunoregulatory, antibacterial, and antioxidant properties for wound healing
|
AuthorQingcong Wei, Zhenhua Fan, Hanwen Chen, Weiwei Zhang, Yuqin Jiang, Zhiguo Hu, Qigang Wang |
Publish_toCARBOHYDRATE POLYMERS |
|
IF12.5000 |
PMID |
Polygonatum cyrtonema Hua polysaccharide alleviates ulcerative colitis via gut microbiota-independent modulation of inflammatory immune response
|
AuthorJin-Yang Shi, Yong-Jian Wang, Qian-Wen Bao, Ya-Min Qin, Pei-Pei Li, Qiao-Qiao Wu, Cheng-Kai Xia, De-Ling Wu, Song-Zi Xie |
Publish_toCARBOHYDRATE POLYMERS |
|
IF12.5000 |
PMID40049966 |
Zexie Tang Polysaccharides (ZXTPs) alleviate high-fat diet-induced NAFL in mice through improving intestinal microbiota imbalance and liver metabolic dysfunction
|
AuthorZhiqiang Zhang, Yanle Zhi, Shengchao Wang, Fengjiao Zhang, Sufeng Zhang, Jiarui Wu |
Publish_toCARBOHYDRATE POLYMERS |
|
IF12.5000 |
PMID |
Bioceramics-enhanced patch activates epicardial epithelial-to-mesenchymal transition via Notch pathway for cardiac repair
|
AuthorChengbin Ding, Chen Qin, Yan Sun, Yueyang Liu, Guofeng Tang, Zhibin Liao, Chaoran Zhao, Chengtie Wu, Leyu Wang |
Publish_toScience Advances |
|
IF12.5000 |
PMID40465713 |
Matrix mechanical remodeled carrier-free nanosystem for programmable closed-loop reversal of liver fibrosis via STING alkylation
|
AuthorHongyun Han, Dongrun Yu, Yuxiang Liu, Huizhen Jia, Wenguang Liu |
Publish_toScience Advances |
|
IF12.5000 |
PMID |
Light-Activatable Nanotherapeutic Platform Synchronizing ROS-Mediated Antibacterial Action with Macrophage Polarization for Refractory Wound Infections
|
AuthorXinyue Guo, Hongru Li, Yu Chen, Zongjia Li, Miaomiao Zhang, Jinyao Zheng, Jiang Li, Xiue Jiang, Jilin Tang |
Publish_toSmall |
|
IF12.1000 |
PMID40801489 |
Macrophage membrane functionalized biomimetic nanoparticles for targeted anti-atherosclerosis applications
|
AuthorYi Wang, Kang Zhang, Tianhan Li, Ali Maruf, Xian Qin, Li Luo, Yuan Zhong, Juhui Qiu, Sean McGinty, Giuseppe Pontrelli, Xiaoling Liao, Wei Wu, Guixue Wang |
Publish_toTheranostics |
|
IF11.5560 |
PMID33391468 |
An oral vaccine based on stable peptide-chitosan conjugate targeting DEC-205 for cancer immunotherapy
|
AuthorMengfan Wang, Xiaoyun Ye, Wanqiong Li, Danhong Chen, Xin Zhao, Peishang Shi, Xinghua Sui, Juan Liu, Feiyu Luo, Xin Yang, Xiaoshuang Niu, Youmei Xiao, Yuzhen Qian, Haoming Ning, Zhuoying He, Huihao Li, Ye Su, Wenxuan Zeng, Guanyu Chen, Yanfeng Gao |
Publish_toJOURNAL OF CONTROLLED RELEASE |
|
IF11.5000 |
PMID |
免疫识别的新局面。 稍加注意不难发现，PAMP很少包括蛋白质。这符合逻辑，因为识别蛋白质抗原的主要是活跃于适应性免疫的淋巴细胞。于是，机体对非己成分的免疫应答落入两个范畴，各自针对病原体相对单一的非蛋白质抗原与较为复杂的蛋白质抗原，并以从简到繁不同的方式逐一实施应答，形成相互有别的反应格局。这正是我们面临的两种免疫：固有免疫和适应性免疫。两者时相上有先后，但相互交替。 PAMP主要成分脂多糖(A)和肽聚糖(B)的结构 Mur(MurNac)：乙酰胞壁酸；Glc(GIcNac)：乙酰
nulidaodi 我做的课题需要用脂多糖来激活MAPK通路，并且分别在激活5m，10m，15m，30m，60m后检测，加入脂多糖的时候应该是在无菌操作台中操作，因为外面空气中有细菌，也就是说有脂多糖，会影响实验结果，在加入脂多糖后，时间点到了，比如说已经到了5m或10m，这时候该如何终止反应呢？用生理盐水清洗然后加入细胞裂解液裂解细胞，是这样地吗？那么这个过程在什么环境中操作呢?如果加入脂多糖到了时间点后就把培养皿拿出超净台，在外面用生理盐水清洗，然后加入细胞
抗体复合物 ，经过彻底洗涤后 加 底物TMB 显色。 TMB 在 HRP 酶的催化下转化成蓝色，并在酸的作用下转化成最终的黄色。颜色的深浅和样品中的 脂多糖 (LPS) 呈正相关。用酶标仪在 450 nm波长下测定吸光度（ OD 值）， 通过标准曲线 计算样品 中 大鼠 脂多糖 (LPS) 浓度。 试剂盒组成 ： 试剂盒组成 48孔配置 96孔配置
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