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- 详细信息
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- 文献和实验
- 技术资料
- 英文名：
ReNcell VM Human Neural Progenitor Cell Line
- 规格：
T25/冻存管
细胞名称：ReNcell VM Human Neural Progenitor Cell Line
货号：SCC008
种属：human
组织来源：人腹侧中脑组织
细胞系描述：神经干细胞
应用：研究类别、干细胞研究
组分：来自人腹侧中脑组织的> 1x10^6个活ReNcell VM细胞，冷冻保存。 储存在液氮中。
质量：已经验证了每批ReNcell VM细胞的巢蛋白和Sox 2的高水平表达及其自我更新和多谱系分化能力。通过染色体扩散评估，细胞还显示出正常的核型，并且支原体测试为阴性。已对孕妇血液进行了HIV、HTLV、乙型和丙型肝炎筛查。
储存及稳定性：当在推荐的储存条件（液氮）下储存时，ReNcell VM细胞在有效期内保持稳定。 请勿暴露于高温下。 到期后，请丢弃所有剩余的试剂。 我们建议在十代内使用细胞。
其他说明：根据产品文件中详述的“学术使用协议”的条款，本产品预期仅用于销售和销售给学术机构，以供内部学术研究使用。
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文献和实验Gracia-Diaz C, Zhou Y, Yang Q, Maroofian R, Espana-Bonilla P, Lee CH, Zhang S, Padilla N, Fueyo R, Waxman EA, Lei S, Otrimski G, Li D, Sheppard SE, Mark P, Harr MH, Hakonarson H, Rodan L, Jackson A, Vasudevan P, Powel C, Mohammed S, Maddirevula S, Alzaidan H, Faqeih EA, Efthymiou S, Turchetti V, Rahman F, Maqbool S, Salpietro V, Ibrahim SH, di Rosa G, Houlden H, Alharbi MN, Al-Sannaa NA, Bauer P, Zifarelli G, Estaras C, Hurst ACE, Thompson ML, Chassevent A, Smith-Hicks CL, de la Cruz X, Holtz AM, Elloumi HZ, Hajianpour MJ, Rieubland C, Braun D, Banka S; Genomic England Research Consortium; French DL, Heller EA, Saade M, Song H, Ming GL, Alkuraya FS, Agrawal PB, Reinberg D, Bhoj EJ, Martínez-Balbás MA, Akizu N. Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders. Nat Commun. 2023 Jul 11;14(1):4109. doi: 10.1038/s41467-023-39645-5. PMID: 37433783; PMCID: PMC10336078.
Yao J, Wu X, Zhang D, Wang L, Zhang L, Reynolds EX, Hernandez C, Boström KI, Yao Y. Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations. J Clin Invest. 2019 Jun 24;129(8):3121-3133. doi: 10.1172/JCI125965. PMID: 31232700; PMCID: PMC6668698.
Stangeland B, Mughal AA, Grieg Z, Sandberg CJ, Joel M, Nygård S, Meling T, Murrell W, Vik Mo EO, Langmoen IA. Combined expressional analysis, bioinformatics and targeted proteomics identify new potential therapeutic targets in glioblastoma stem cells. Oncotarget. 2015 Sep 22;6(28):26192-215. doi: 10.18632/oncotarget.4613. PMID: 26295306; PMCID: PMC4694895.
Shah K, King GD, Jiang H. A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells. J Mol Cell Biol. 2020 Jan 22;12(1):4-16. doi: 10.1093/jmcb/mjz036. PMID: 31065682; PMCID: PMC7052987.
We document the protocols and methods for the production of immortalized cell lines of human neural stem cells from the human fetal central nervous system (CNS) cells by using a retroviral vector encoding v-myc oncogene. One of the human
Protocols for Investigating microRNA Functions in Human Neural Progenitor Cells
. Here we present experimental protocols for investigating the endogenous functions of specific miRNAs in the proliferation, survival, and migration of human neural progenitor cells derived from embryonic stem cells. These methods may be applicable to protein
to assess the neural progenitor (NP) generation of human pluripotent stem cell lines. This method includes a robust and well-defined neural inducing platform for Pax6+ neural rosette (neuroectodermal cells) generation, propagation, and subsequent
