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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human
- 亚型:
IgG-like
- 形态:
Liquid
- 保存条件:
/
- 克隆性:
Monoclonal
- 适应物种:
/
- 保质期:
1 year
- 抗原来源:
Human
- 目录编号:
HV612086
- 级别:
科研级别
- 库存:
999
- 供应商:
abinscience
- 宿主:
Human
- 应用范围:
Research Grade Biosimilar
- 浓度:
1mg/ml
- 靶点:
CD276 antigen, 4Ig-B7-H3, B7 homolog 3, B7-H3, Costimulatory molecule, CD276, CD276, Epidermal growth factor receptor, EC:2.7.10.1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR
- 抗体英文名:
Research Grade Anti-B7-H3 & EGFR Bispecific Antibody (Ibi-334)
- 抗体名:
Research Grade Anti-B7-H3 & EGFR Bispecific Antibody (Ibi-334)
- 规格:
100ug
| Product name | Research Grade Anti-B7-H3 & EGFR Bispecific Antibody (Ibi-334) |
|---|---|
| Catalog No. | HV612086 |
| Host species | Human |
| Species reactivity | Human |
| Immunogen | / |
| Form | Liquid |
| Storage buffer | / |
| Purity | >95% purity as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | IgG-like |
| Applications | Research Grade Biosimilar |
| Target | CD276 antigen, 4Ig-B7-H3, B7 homolog 3, B7-H3, Costimulatory molecule, CD276, CD276, Epidermal growth factor receptor, EC:2.7.10.1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EGFR |
| Purification | Protein A/G, purified from cell culture supernatant. |
| Endotoxin level | Please contact the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | Q5ZPR3 & P00533 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternative Names | Ibi334, Ibi 334 |
| Clone ID | Ibi-334 |
| Species | / |
| Note | For research use only. Not for use in clinical or therapeutic applications. |
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文献和实验Shanker, Varun R et al. “Unsupervised evolution of protein and antibody complexes with a structure-informed language model.” Science (New York, N.Y.) vol. 385,6704 (2024): 46-53. doi:10.1126/science.adk8946
【翻译】Development trends for monoclonal antibody cancer therapeutics
, after binding to a target, mAbs can recruit effector cells such as natural killer cells, macrophages or neutrophils, or activate complement to destroy the target3, 24, 25, 26, 27. These two modes of action are referred to as antibody-dependent cell cytotoxicity
secondary antibody review -- data from 99 publications
cytometry used as a control to detect cell responses targeted antigen 7 Alexa Fluor 488 7 Cy3 8 goat IgG Alexa Fluor 488 1:2000 detect antibody binding in human embryonic kidney 293T cells Invitrogen 9 donkey
Immuno-Laser Capture Microdissection
) Superfrost Plus glass slides (Fisher Scientific) Placental RNase inhibitor (Perkin Elmer, Branchburg) DEPC-treated H 2 O (Research Genetics) Important: Add placental RNase inhibitor to the primary antibody
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