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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
详询
- 保质期:
详询
- 英文名:
Immunotag™ Cytochrome P450 2C19 Antibody-Alexa Fluor® 350*
- 库存:
99
- 供应商:
北京孚博生物
- CAS号:
详询
- 规格:
100ug
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文献和实验In Vitro Identification of Cytochrome P450 Enzymes Responsible for Drug Metabolism
Metabolism catalyzed by the cytochrome P450 enzymes (CYPs) represents the most important pathway for drug metabolism and elimination in humans. Identification of the CYPs responsible for metabolism of existing and novel drugs is critical
以花青或罗丹明染料为核心结构,该核心结构的特殊化学修饰限制了染料的分子内位移,从而获得染料的高量子产率和更好的水溶性。因此,近红外CF染料比其他近红外染料荧光强度更高,光稳定性好。最重要的是,在免疫印迹实验上应用近红外CF染料标记蛋白质样品相对于其他商业用近红外染料制备的抗体偶联物,最大限度的提高了信噪比。 3、优异的标记效率 生物偶联后的活性染料一般很容易水解,会在运输,操作及储存中带来诸多不便,最终致染料结合效率低下。像Alexa Fluor®dyes,DyLight™dyes
DMET Microarray Technology for Pharmacogenomics-Based Personalized Medicine
can be influenced by a cytochrome P450 (CYP) 4F2 variant. Additionally, the assay has been used to demonstrate that CYP2C19 variants with decreased enzyme activity led to lower levels of the active clopidogrel metabolite, resulting in a decreased inhibition
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