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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
详询
- 保质期:
详询
- 英文名:
IL-1RAcP (C2) Peptide
- 库存:
99
- 供应商:
北京孚博生物
- CAS号:
详询
- 规格:
0.05mg
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文献和实验Activating the NLRP3 Inflammasome Using the Amyloidogenic Peptide IAPP
an inflammasome complex that ultimately cleaves pro-IL-1β and pro-IL-18 into their mature, secreted forms. Here we describe a protocol by which one type of amyloidogenic peptide, islet amyloid polypeptide (IAPP, otherwise known as amylin) can be prepared and used
【进展|热点】银屑病新机制——science杂志上的最新文章
2, and cytosolic DNA triggered the re- lease of IL-1 via the AIM2 inflammasome. Moreover, the antimicrobial cathelicidin peptide LL-37, which can inter- act with DNA in psoriatic skin, neutralized cytosolic DNA in keratinocytes and blocked AIM2 inflammasome
greater selectivity for JNK as compared to ERK1 and p38-2 MAP kinases. Inhibits the phosphorylation of c-Jun and blocks cellular expression of IL-2, IFN-γ, TNF-α, and COX-2. Blocks IL-1-induced accumulation of phospho-Jun and induction of c-Jun
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