A-431细胞系

【A-431】A-431细胞/A-431细胞/A-431人表皮癌细胞Cell line name A-431

Synonyms A431; A431/P

Accession CVCL_0037

Resource Identification Initiative To cite this cell line use: A-431 (RRID:CVCL_0037)

Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).

Part of: COSMIC cell lines project.

Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).

Population: Caucasian.

Doubling time: ~80-100 hours (DSMZ=ACC-91).

Karyotypic information: Hypertriploid karyotype (ATCC=CRL-1555).

Microsatellite instability: Stable (MSS) (Sanger).

Omics: Cell surface proteome.

Omics: Deep antibody staining analysis.

Omics: Deep exome analysis.

Omics: Deep phosphoproteome analysis.

Omics: Deep proteome analysis.

Omics: Deep quantitative proteome analysis.

Omics: DNA methylation analysis.

Omics: HLA class I peptidome analysis by proteomics.

Omics: SNP array analysis.

Omics: Transcriptome analysis by microarray.

Omics: Transcriptome analysis by RNAseq.

Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.

PubMed=212188

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Evaluating the promiscuous nature of tyrosine kinase inhibitors assessed in A431 epidermoid carcinoma cells by both chemical- and phosphoproteomics.

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Integrin signalling regulates YAP and TAZ to control skin homeostasis.

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