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T25
COS7、COS-7、COS7细胞、COS-7细胞、COS-7非洲绿猴肾成纤维细胞（SV40转化）
Cell line name COS-7
Synonyms Cos-7; COS 7; Cos 7; COS7; Cos7; CV-1 in Origin Simian-7
Accession CVCL_0224
Resource Identification Initiative To cite this cell line use: COS-7 (RRID:CVCL_0224)
Comments Group: Non-human primate cell line.
Virology: Highly susceptible to infection by Zika virus (ZIKV) (PubMed=29468137).
Doubling time: ~35-48 hours (DSMZ=ACC-60); ~2 days (Note=Lot 03052018) (JCRB=IFO50068); ~34 hours (Note=Lot 02292000), ~30 hours (Note=Lots 11222004 and 10052007) (JCRB=JCRB9127).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV6-1).
Misspelling: COS-2; Note=Thanks to a personal communication of Galan, Jorge E. we we made aware that COS-2 was mistakenly used instead of COS-7 in 3 papers: PubMed=14662750, PubMed=17074883 and PubMed=19379694.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534)
Hierarchy Parent: CVCL_0229 (CV-1)
Children:
CVCL_A5PZ (COS-7 1C7) CVCL_LH58 (COS-7 1E7) CVCL_Z935 (COS-7-InVitrus)
CVCL_0J76 (COS-7L) CVCL_E071 (COS/Fucci) CVCL_B7HB (COS7-moRIII)
CVCL_B7HC (COS7 moRIII-gamma) CVCL_B7HD (COS7-pc) CVCL_YJ78 (LINTERNA COS-7)
CVCL_D2UH (PDIS-4)
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
PubMed=6260373; DOI=10.1016/0092-8674(81)90282-8
Gluzman Y.
SV40-transformed simian cells support the replication of early SV40 mutants.
Cell 23:175-182(1981)
PubMed=22059503; DOI=10.1186/1472-6750-11-102; PMCID=PMC3221628
Almeida J.L., Hill C.R., Cole K.D.
Authentication of African green monkey cell lines using human short tandem repeat markers.
BMC Biotechnol. 11:102.1-102.10(2011)
PubMed=29468137; DOI=10.5501/wjv.v7.i1.10; PMCID=PMC5807893
Himmelsbach K., Hildt E.
Identification of various cell culture models for the study of Zika virus.
World J. Virol. 7:10-20(2018)
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文献和实验*发表【中文论文】请标注：由博辉生物科技（广州）有限公司提供； *发表【英文论文】请标注：From Bohui Biological Technology (Guangzhou) Co., Ltd.
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