C8-D1A细胞

C8-D1A/C8-D1A细胞系/C8-D1A细胞株/C8-D1A小鼠小脑细胞

Cell line name    C8-D1A
Synonyms    C8D1A; Astrocyte type I clone
Accession    CVCL_6379
Resource Identification Initiative    To cite this cell line use: C8-D1A (RRID:CVCL_6379)
Comments    Characteristics: Susceptible to infection by mouse scrapie prion (PrPSc) strains 22L and RML (PubMed=32561641).
Omics: Deep proteome analysis.
Omics: Secretome proteome analysis.
Derived from site: In situ; Brain, cerebellum; UBERON=UBERON_0002037.
Cell type: Astrocyte of cerebellum; CL=CL_0002603.
Species of origin    Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Sex of cell    Sex unspecified
Age at sampling    8D
Category    Spontaneously immortalized cell line
Publications    
PubMed=6466977; DOI=10.1016/0006-8993(84)90377-9
Alliot F., Pessac B.
Astrocytic cell clones derived from established cultures of 8-day postnatal mouse cerebella.
Brain Res. 306:283-291(1984)

PubMed=24753479; DOI=10.1002/pmic.201300495
Han D.-H., Jin J.-H., Woo J.-M., Min H., Kim Y.-S.
Proteomic analysis of mouse astrocytes and their secretome by a combination of FASP and StageTip-based, high pH, reversed-phase fractionation.
Proteomics 14:1604-1609(2014)

PubMed=26227174; DOI=10.1002/pmic.201400623
Woo J.-M., Han D.-H., Park J.-H., Kim S.-J., Kim Y.-S.
In-depth characterization of the secretome of mouse CNS cell lines by LC-MS/MS without prefractionation.
Proteomics 15:3617-3622(2015)

PubMed=32561641; DOI=10.1074/jbc.RA120.012596; PMCID=PMC7450132
Tahir W., Abdulrahman B., Abdelaziz D.H.A., Thapa S., Walia R., Schatzl H.M.
An astrocyte cell line that differentially propagates murine prions.
J. Biol. Chem. 295:11572-11583(2020)