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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
本品可在2-8°C保存12个月。请避免长期接触阳光,不要冻结。
- 保质期:
12个月
- 规格:
20Tests/100Tests/100Tests×2
| 规格: | 20Tests | 产品价格: | ¥1560.0 |
|---|---|---|---|
| 规格: | 100Tests | 产品价格: | ¥3600.0 |
| 规格: | 100Tests×2 | 产品价格: | ¥6480.0 |
| Alternate Names |
DNAM-1, PTA1, TLiSA1
|
| Cellular Localization |
Membrane
|
| Clone No |
11A8
|
| Isotype |
Mouse IgG1, κ
|
| Leadtime |
咨询
|
| Background |
DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells, monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a member of the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-set. The ligands for CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), which are broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physically associated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediated signaling.
|
| Abbre |
CD226
|
| Swissprot |
Q15762
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Clonality |
Monoclonal
|
| Isotype Control |
Elab Fluor®700 Mouse IgG1, κ Isotype Control[MOPC-21]
|
| Applications |
FCM
|
| Form |
Liquid
|
| Conjugation |
Elab Fluor®700
|
| Conjugation Information |
Elab Fluor® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration Date |
12个月
|
| Shipping |
冰袋
|
| Gene ID |
10666
|
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
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文献和实验Immune Response Biomarker Profiling
a total of 5 wash steps. 8) During the wash steps, mix 2.5 L Alexa Fluor® 647 goat anti-human IgG antibody with 5 mL Washing Buffer per array to obtain a final antibody concentration of 1 g/mL. Store on ice until use. Optional: add Alexa Fluor®®
不只是 PD-1:CD96 正成为免疫治疗的下一个“必争之地”
结合的关键区域 [8]。CD155 同样属于 Ig 超家族,其胞外区由三个 Ig 样结构域组成,CD96 主要通过自身 IgV 结构域与 CD155 的 N 端 IgV 结构域相互识别 [8]。 3.2 CD96、TIGIT、CD226 免疫调控网络 CD96、TIGIT 和共刺激受体 CD226(DNAM-1)共同构成一个复杂的免疫调控网络,它们共享 CD155 和 CD112 等配体,在免疫激活与抑制之间形成动态平衡 [1],[9]。其中,TIGIT 可与 CD155 和 CD112 结合
Reprogramming Fibroblasts with the CytoTune-iPS Reprogramming Kit
4 Antibody 22. Rabbit Anti-SeV Antibody 23. Alexa Fluor® 488 Goat Anti-Mouse IgG (H L) Antibody 24. Alexa Fluor® 594 Goat Anti-Mouse IgG (H L) Antibody 25. Alexa Fluor® 488 Goat Anti-Rabbit IgG (H L) Antibody 26. Alexa Fluor® 594
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