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- 富衡生物
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- FH1013
- 2026年03月27日
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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
16HBE HBE135-E6E7 (ATCC® CRL-2741)
- 库存：
复苏：1-2周。冻存：现货。（建议:复苏为主，极个别特殊情况选冻存）
- 供应商：
上海富衡生物科技有限公司
- 肿瘤类型：
非肿瘤
- 细胞类型：
真核细胞
- 品系：
人源支气管上皮细胞系（正常）
- 组织来源：
正常肺组织
- 相关疾病：
正常支气管上皮细胞（无特定疾病关联，常用于呼吸道研究）
- 物种来源：
人源
- 免疫类型：
非免疫细胞
- 细胞形态：
上皮样
- 是否是肿瘤细胞：
否
- 器官来源：
肺
- 运输方式：
常温/干冰，快递运输
- 年限：
数年
- 生长状态：
贴壁生长
- 规格：
1 × 10⁶ cells/T25 flask/冻存管
| 规格： | 1 × 10⁶ cells/T25 flask | 产品价格： | ￥1700.0 |
|---|---|---|---|
| 规格： | 冻存管 | 产品价格： | ￥2000.0 |
16HBE 和 HBE135-E6E7 是两种广泛应用于呼吸道研究的永生化支气管上皮细胞系，它们通过不同方式实现永生化，具有各自独特的优势和应用场景。16HBE因 SV40 与 CFTR 基因整合而成为研究囊性纤维化的重要模型；HBE135-E6E7则因来源于肺癌患者而在肺癌发生机制研究中具有特殊价值。
| 产品名称 | 人支气管上皮样细胞；16HBE HBE135-E6E7[ATCC® CRL-2741](STR) |
|---|---|
| 品牌 | FuHeng |
| 英文名 | 16HBE HBE135-E6E7 [ATCC® CRL-2741] |
| 货号 | FH1013 |
| 规格 | 1 × 10⁶ cells/T25 flask |
| 培养 | 角质形成细胞培养基(KM) + 0.005 mg/mL 胰岛素 + 500 ng/mL 氢化可的松 |
| 别称 | 16HBE HBE135-E6E7 (ATCC® CRL-2741) |
| 形态特征 | 上皮样 |
| 生长特性 | 贴壁生长 |
| 培养基 | 16HBE HBE135-E6E7专用培养基 |
| 培养条件 | 气相：95% 空气，5% CO₂；温度：37 ℃ |
| 传代方法 | 1:2传代 |
| 组织来源 | 正常肺组织 |
| 产品分类 | 人源细胞系 |
| 特别声明 | 富衡细胞库承诺尽最大努力对实验细胞资源相关信息进行及时更新。但限于当时的技术条件，细胞库资料不保证其准确性。 |
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文献和实验该产品被引用文献
| 论文标题 | DOI | 发表时间 | 期刊 | 影响因子 | 作者列表 |
| Interleukin-17D Attenuates OVA-induced Airway Inflammation and Remodeling Partially via the CD93 Receptor | 10.4168/aair.2025.17.5.592 | 2025-09-05 | Allergy Asthma & Immunology Research | 4.3 | Shuochuan Shi, Jintao Zhang, Yun Pan, Xiaofei Liu, Rong Zeng, Changjuan Xu, Ying Wang, Qian Qi, Zhi Guo, Chengfang Yao, Ju Liu, Jianwen Fei, Li Li, Liang Dong |
| Exploring the role of ELOVLs family in lung adenocarcinoma based on bioinformatic analysis and experimental validation | 10.1186/s12885-024-13415-y | 2025-01-10 | BMC CANCER | 3.4 | Wang Zihan, Cui Wenjing, Liang Long, Qu Jingge, Pei Yuqiang, Li Danyang, Luo Ying, Zhang Yue, Qiu Yifan, Sun Yongchang |
| Enhancing Student Comprehension of Glucose Metabolism Visualization Through Virtual Simulation Platform: An Educational Approach | 10.1002/prp2.70042 | 2024-11-27 | Pharmacology Research & Perspectives | 2.9 | Luna Ge, Tingting Feng, Shuo Cao, Hang Yin, Yuang Zhang, Jihong Pan, Wei Chen, Kai Cheng, Lin Wang |
| Unleashing AdipoRon’s Potential: A Fresh Approach to Tackle Pseudomonas aeruginosa Infections in Bronchiectasis via Sphingosine Metabolism Modulation | 10.2147/JIR.S483689 | 2024-10-23 | Journal of Inflammation Research | 4.2 | Jia-wei Xu, Fang-fang Chen, Ying-hui Qv, Cong-cong Sun, Dong Zhang, Zhi Guo, Yu-jiao Wang, Jun-fei Wang, Tian Liu, Liang Dong, Qian Qi |
| PM2.5 Exposure Aggravates Inflammatory Response and Mucus Production in 16HBE Cells through Inducing Oxidative Stress and RAGE Expression | 10.1007/s12013-024-01526-z | 2024-09-19 | CELL BIOCHEMISTRY AND BIOPHYSICS | 1.8 | Han Huishan, Peng Xianru, Huang Minyu, Zhao Wenqu, Yang Shuluan, Lan Zihan, Cai Shaoxi, Zhao Haijin |
| PKHD1L1 blocks the malignant behavior of lung adenocarcinoma cells and restricts tumor growth by regulating CBX7 | 10.32604/biocell.2024.049626 | 2024-08-02 | BIOCELL | 0.8 | KEWEI CHENG, LEI SHI, CAIWEN SHI, SHUANSHUAN XIE, CHANGHUI WANG |
| Targeting lysyl oxidase like 2 attenuates OVA-induced airway remodeling partly via the AKT signaling pathway | 10.1186/s12931-024-02811-4 | 2024-06-01 | RESPIRATORY RESEARCH | 4.7 | Zeng Rong, Zhang Dong, Zhang Jintao, Pan Yun, Liu Xiaofei, Qi Qian, Xu Jiawei, Xu Changjuan, Shi Shuochuan, Wang Junfei, Liu Tian, Dong Liang |
| Semaphorin 7a aggravates TGF-β1-induced airway EMT through the FAK/ERK1/2 signaling pathway in asthma | 10.3389/fimmu.2023.1167605 | 2023-11-01 | Frontiers in Immunology | 7.3 | Haiying Peng, Fei Sun, Yunxiu Jiang, Zihan Guo, Xinyi Liu, Anli Zuo, Degan Lu |
| Suppression of SPARC Ameliorates Ovalbumin-induced Airway Remodeling via TGFβ1/Smad2 in Chronic Asthma | 10.4168/aair.2024.16.1.91 | 2023-08-18 | Allergy Asthma & Immunology Research | 4.4 | Yun Pan, Dong Zhang, Jintao Zhang, Xiaofei Liu, Jiawei Xu, Rong Zeng, Wenjing Cui, Tian Liu, Junfei Wang, Liang Dong |
| Targeted therapy for cisplatin-resistant lung cancer via aptamer-guided nano-zinc carriers containing USP14 siRNA | 10.1002/mco2.237 | 2023-04-06 | MedComm | 9.9 | Xinmin Zhao, Xianghua Wu, Huijie Wang, Songtao Lai, Jialei Wang |
| A positive feedback circuit between RN7SK snRNA and m6A readers is essential for tumorigenesis | 10.1016/j.ymthe.2022.12.013 | 2022-12-24 | MOLECULAR THERAPY | 12.9 | Xin Xu, Lifang Ma, Xiao Zhang, Susu Guo, Wanxin Guo, Yikun Wang, Shiyu Qiu, Xiaoting Tian, Yayou Miao, Yongchun Yu, Jiayi Wang |
| Integrated Clinical and Prognostic Analysis of the m6A RNA Methylation Regulator YTHDF3 in Pan-Cancer and its Correlation with Cancer Cell Proliferation | 10.7150/jca.78403 | 2022-11-21 | Journal of Cancer | 4.5 | Cao Leiqun, Zeng Bingjie, Wang Yulan, Wang Xianzhao, Qin Yueyang, Zhang Congcong, Wu Mengyi, Wang Jiayi, Zhang Xiao, Ma Lifang |
| Anemoside B4 prevents chronic obstructive pulmonary disease through alleviating cigarette smoke-induced inflammatory response and airway epithelial hyperplasia | 10.1016/j.phymed.2022.154431 | 2022-09-02 | PHYTOMEDICINE | 6.7 | Huimiao Ma, Ziye Zhou, Lanying Chen, Lingling Wang, Qi Muge |
| Estradiol inhibits autophagy of Mycobacterium tuberculosis‑infected 16HBE cells and controls the proliferation of intracellular Mycobacterium tuberculosis | 10.3892/mmr.2022.12712 | 2022-04-15 | Molecular Medicine Reports | 3.4 | Yiling Gan, Qianfang Hu, Anmao Li, Lei Gu, Shuliang Guo |
| Construction of lncRNA-Mediated Competing Endogenous RNA Networks Correlated With T2 Asthma. | 10.3389/fgene.2022.872499 | 2022-04-11 | Frontiers in Genetics | 4.8 | Zihan Wang, Jintao Zhang, Tao Feng, Dong Zhang, Yun Pan, Xiaofei Liu, Jiawei Xu, Xinrui Qiao, Wenjing Cui, Liang Dong |
| ELK1 Promotes Epithelial-Mesenchymal Transition and the Progression of Lung Adenocarcinoma by Upregulating B7-H3 | 10.1155/2021/2805576 | 2021-12-21 | Oxidative Medicine and Cellular Longevity | 6.5 | Ting-ting Yu, Tao Zhang, Fei Su, Ying-long Li, Li Shan, Xiao-ming Hou, Ruo-zheng Wang |
| miR‑29a‑3p regulates the epithelial‑mesenchymal transition via the SPARC/ERK signaling pathway in human bronchial epithelial cells | 10.3892/ijmm.2021.5004 | 2021-07-12 | INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE | 4.1 | Xiaobo Zhang, Jun Xie, Hongmei Sun, Qin Wei, Guangmin Nong |
| Targeting SLC3A2 subunit of system XC− is essential for m6A reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma | 10.1016/j.freeradbiomed.2021.03.023 | 2021-03-27 | FREE RADICAL BIOLOGY AND MEDICINE | 7.4 | Lifang Ma, Xiao Zhang, Keke Yu, Xin Xu, Tianxiang Chen, Yi Shi, Yikun Wang, Shiyu Qiu, Susu Guo, Jiangtao Cui, Yayou Miao, Xiaoting Tian, Lutao Du, Yongchun Yu, Jinjing Xia, Jiayi Wang |
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人支气管上皮样细胞；16HBE HBE135-E6E7[ATCC® CRL-2741](STR)
￥1700 - 2000
