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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 英文名：
Lieming Xu-2
- 库存：
复苏：1-2周。冻存：现货。（建议:复苏为主，极个别特殊情况选冻存）
- 供应商：
上海富衡生物科技有限公司
- 肿瘤类型：
非肿瘤
- 细胞类型：
真核细胞
- 品系：
人源肝星状细胞系
- 组织来源：
肝组织
- 相关疾病：
正常肝星状细胞（无特定疾病关联，常用于肝纤维化研究）
- 物种来源：
人源
- 免疫类型：
非免疫细胞
- 细胞形态：
星状细胞样
- 是否是肿瘤细胞：
否
- 器官来源：
肝脏
- 运输方式：
常温/干冰，快递运输
- 年限：
数年
- 生长状态：
贴壁生长
- 规格：
1 × 10⁶ cells/T25 flask/冻存管
| 规格： | 1 × 10⁶ cells/T25 flask | 产品价格： | ￥1200.0 |
|---|---|---|---|
| 规格： | 冻存管 | 产品价格： | ￥1500.0 |
LX-2细胞系由科学家Lieming Xu等人于2005年建立，旨在解决原代肝星状细胞培养中存在的获取困难、批次间变异大等问题。LX-2细胞是一种非常重要的人源肝星状细胞系，在肝脏疾病研究，特别是肝纤维化的机制探索和药物研发中扮演着核心角色。
| 产品名称 | 人肝星形细胞；LX-2(STR) |
|---|---|
| 品牌 | FuHeng |
| 英文名 | LX-2 |
| 货号 | FH0108 |
| 规格 | 1 × 10⁶ cells/T25 flask |
| 培养 | DMEM + 10% FBS + 1% P/S |
| 别称 | Lieming Xu-2 |
| 形态特征 | 星状细胞样 |
| 生长特性 | 贴壁生长 |
| 培养基 | LX-2完全培养基 |
| 培养条件 | 气相：95% 空气，5% CO₂；温度：37 ℃ |
| 传代方法 | 1:3传代，2-3天换液一次。 |
| 组织来源 | 肝组织 |
| 产品分类 | 人源细胞系 |
| 特别声明 | 富衡细胞库承诺尽最大努力对实验细胞资源相关信息进行及时更新。但限于当时的技术条件，细胞库资料不保证其准确性。 |
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- 作者
- 内容
- 询问日期
文献和实验该产品被引用文献
| 论文标题 | DOI | 发表时间 | 期刊 | 影响因子 | 作者列表 |
| Curcumol ameliorates high-fat diet-induced hepatic fibrosis via dual regulation of FXR-CREB and Rab18-mediated hepatic stellate cell lipophagy | 10.1016/j.bbalip.2025.159710 | 2025-12-11 | BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS | 3.3 | Na Wei, Wanyu Feng, Meijun Pan, Xinyi Xu, Shuguo Zheng, Huanhuan Jin |
| Fibroblast growth factor receptor inhibitors ameliorate metabolic dysfunction-associated steatohepatitis by modulating the glycine-glutathione-gut microbiota axis | 10.1016/j.freeradbiomed.2025.08.044 | 2025-08-21 | FREE RADICAL BIOLOGY AND MEDICINE | 8.2 | Hailong Li, Xiaoman Ye, Yayue Hu, Yingjun Wang, Yuting Ding, Ying Yang, Ruiqi Mao, Xi Wu, Huixuan Dong, Kaijun Qiu, Xiaohe Li, Honggang Zhou, Guang Yang, Fubao Zhang, Cheng Yang |
| M6PR upregulation by berberine attenuates hepatic senescence via sorting STING into endosome for degradation | 10.1016/j.phymed.2025.157089 | 2025-07-25 | PHYTOMEDICINE | 8.3 | Wenjuan Tang, Qianqian Zhang, Longyu Qin, Xinxin Yang, Dake Chu, Han Li, Jiaqi Zhang, Yanmin Zhang, Hongmei Zhang |
| Micheliolide Alleviates Hepatic Fibrosis by Inhibiting Autophagy in Hepatic Stellate Cells via the TrxR1/2-Mediated ROS/MEK/ERK Pathway | 10.3390/ph18030287 | 2025-02-20 | Pharmaceuticals | 4.8 | Yi Liu, Ling Yao, Yuanyuan Liu, Yunheng Yang, Ailing Liang, Honglin He, Yao Lei, Wenfu Cao, Zhiwei Chen |
| Hepatoprotective action mechanism and quantification of soyasaponin Bb in Abri Herba by HPLC and network pharmacology | 10.1016/j.jep.2024.118850 | 2024-09-24 | JOURNAL OF ETHNOPHARMACOLOGY | 4.8 | Xingmei Lin, Chengzhong Zhang, Baokang Huang |
| Hepatoprotective effect of diammonium glycyrrhizinate and neuroprotective effect of piperazine ferulate on AmB-induced liver and kidney injury by suppressing apoptosis in vitro and in vivo | 10.1016/j.toxicon.2024.107795 | 2024-06-05 | TOXICON | 2.6 | Xu He, Xiuhong Peng, Suyu Zhang, Tianfeng Yang, Jian Huo, Yanmin Zhang |
| Paeoniflorin promotes PPARγ expression to suppress HSCs activation by inhibiting EZH2-mediated histone H3K27 trimethylation | 10.1016/j.phymed.2024.155477 | 2024-02-24 | PHYTOMEDICINE | 6.7 | Tian Lan, Ping Li, Si-jia Zhang, Shi-yu Liu, Xi-xi Zeng, Fang Chai, Yu-hua Tong, Zhu-jun Mao, Si-wei Wang |
| Echinacoside Exerts Antihepatic Fibrosis Effects in High-Fat Mice Model by Modulating the ACVR2A-Smad Pathway | 10.1002/mnfr.202300553 | 2024-02-17 | MOLECULAR NUTRITION & FOOD RESEARCH | 4.5 | Jie Liang, Ting Chen, Honglei Xu, Tingfang Wang, Qi Gong, Tingting Li, Xiaoyan Liu, Jing Wang, Yun Wang, Liyan Xiong |
| A three-dimensional (3D) liver–kidney on a chip with a biomimicking circulating system for drug safety evaluation | 10.1039/D3LC00980G | 2024-01-31 | LAB ON A CHIP | 6.1 | Qihong Huang, Tianhao Yang, Yunpeng Song, Wenxuan Sun, Jian Xu, Ya Cheng, Ruixue Yin, Lili Zhu, Mengting Zhang, Lei Ma, Honglin Li, Hongbo Zhang |
| Serum exosome-derived microRNA-193a-5p and miR-381-3p regulate AMPK/TGF-β/Smad2/3 signaling pathway and promote fibrogenesis | 10.14309/ctg.0000000000000662 | 2023-12-15 | Clinical and Translational Gastroenterology | 3.6 | Wang Sihao, Chen Yan, Lei Guanglin, Ma Xuemei, An Linjing, Wang Han, Song Zheng, Lin Li, He Quanwei, Xu Ran, Zhan Xiaoyan, Bai Zhaofang, Yang Yongping |
| Analysis of bioactive components and synergistic action mechanism of ShuGan-QieZhi Capsule for treating non-alcoholic fatty liver disease | 10.1016/j.phymed.2023.155173 | 2023-10-29 | PHYTOMEDICINE | 7.9 | Tong Zhu, Xiaohui Huang, Hongyan Zhu, Jihui Chen, Huijuan Yao, Yufeng Zhang, Haibing Hua, Jian Zhang, Jia Qi |
| Hydronidone ameliorates liver fibrosis by inhibiting activation of hepatic stellate cells via Smad7-mediated degradation of TGFβRI | 10.1111/liv.15715 | 2023-08-28 | LIVER INTERNATIONAL | 6.7 | Xianjun Xu, Yuecheng Guo, Xin Luo, Zhenyang Shen, Zhongshang Sun, Bo Shen, Cui Zhou, Junjun Wang, Jingyi Lu, Qingqing Zhang, Yanping Ye, Ying Luo, Ying Qu, Xiaobo Cai, Hui Dong, Lungen Lu |
| Schizandrin C regulates lipid metabolism and inflammation in liver fibrosis by NF-κB and p38/ERK MAPK signaling pathways | 10.3389/fphar.2023.1092151 | 2023-05-23 | Frontiers in Pharmacology | 5.6 | Panpan Chen, Rong Wang, Fangbin Liu, Shengnan Li, Yanqiu Gu, Lei Wang, Yongfang Yuan |
| Schisandrin B promotes senescence of activated hepatic stellate cell via NCOA4-mediated ferritinophagy | 10.1080/13880209.2023.2189908 | 2023-04-03 | PHARMACEUTICAL BIOLOGY | 3.8 | Mingyue Ma, Na Wei, Jieren Yang, Tingting Ding, Anping Song, Lerong Chen, Shuguo Zheng, Huanhuan Jin |
| The total polyphenolic glycoside extract of Lamiophlomis rotata ameliorates hepatic fibrosis through apoptosis by TGF-β/Smad signaling pathway | 10.1186/s13020-023-00723-x | 2023-02-24 | Chinese Medicine | 4.9 | Wan Guoguo, Chen Zhiwei, Lei Lei, Geng Xiaoyu, Zhang Yi, Yang Congwen, Cao Wenfu, Pan Zheng |
| Salvianolic acid B suppresses hepatic stellate cell activation and liver fibrosis by inhibiting the NF-κB signaling pathway via miR-6499-3p/LncRNA-ROR | 10.1016/j.phymed.2022.154435 | 2022-09-05 | PHYTOMEDICINE | 6.7 | Rong Wang, Shengnan Li, Panpan Chen, Xin Yue, Shaozhan Wang, Yanqiu Gu, Yongfang Yuan |
| Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation | 10.3892/mmr.2021.11944 | 2021-02-26 | Molecular Medicine Reports | 3.0 | He-Ming Huang, Xiao-Ru Zhou, Yan-Jun Liu, Shi-Jie Fan, Li-Ping Liao, Jing Huang, Cui-Cui Shi, Liang Yu, Jin-Jin Pen, Cheng Luo, Yuan-Yuan Zhang, Guang-Ming Li |
相关实验
polymorphic Y chromosome-specific short tandem repeats (STRs) have been described and a set of 9 loci were selected, considered as the minimal haplotype included in the forensic databases, Y-STR Haplotype Reference Databases, the largest now available online
Constructing STR Multiplex Assays
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据统计约 30% 细胞系被交叉污染或错误辨识，因使用了交叉污染或错误辨识的细胞而导致研究结论错误、结果不可重复、临床细胞治疗灾难性后果……，这浪费大量时间、精力和金钱。Everything was going along fine until they discovered their HeLa cell line expressed Y chromosome markers因此近年 NIH、ATCC、Nature 和 Science 等对此多次发出呼吁，要求研究者对细胞进行鉴定。STR 基因
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人肝星形细胞；LX-2(STR)
￥1200 - 1500
