- 询价
- DIMA
- DME913224
- 2025年07月12日
- Mouse
- Human, Mouse
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- 亚型：
IgG1
- 形态：
请咨询
- 保存条件：
Store at -20°C
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse
- 保质期：
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- 级别：
仅用于科研
- 库存：
1 week
- 宿主：
Mouse
- 浓度：
请咨询
- 靶点：
Ribonuclease H2, subunit A
- 规格：
100ul
| 背景 | The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.[provided by RefSeq, Aug 2009] |
|---|---|
| 别名 | AGS4; JUNB; RNASEHI; RNHIA; RNHL; THSD8 |
| 推荐稀释比 | WB 1:500-1:2000 |
| 组分&重悬 | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| 纯化 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Uniprot ID | O75792 |
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文献和实验Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers
Detection of apoptotic process in situ using immunocytochemical and TUNEL assays
from invertebrates to lower and higher verterbrates, and intervenes both in physiological and in pathological states, such as normal cell turnover, embryogenesis, metamorphosis, thymic maturation and involution, neoplasm, etc. (1-4). A mouse anti-DNA monoclonal
Therapeutic Human Monoclonal Antibodies in Inflammatory Diseases
almost any cell surface or secreted molecule with remarkable efficacy and safety. In this chapter, the application of human mAbs in the treatment of inflammatory diseases is reviewed. We discuss in detail several mAb-based drugs such as anti-tumor necrosis factor
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