- 询价
- DIMA
- DME904858
- 2025年07月16日
- Mouse
- Human, Mouse, Rat
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- 技术资料
- 亚型：
IgG1
- 形态：
请咨询
- 保存条件：
Store at -20°C
- 标记物：
Unconjugated
- 适应物种：
Human, Mouse, Rat
- 保质期：
请咨询
- 级别：
仅用于科研
- 库存：
1 week
- 宿主：
Mouse
- 浓度：
请咨询
- 靶点：
ERG
- 规格：
100ul
| 背景 | This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan |
|---|---|
| 别名 | erg-3; p55 |
| 推荐稀释比 | WB 1:4000, IHC 1:150, IF 1:100 |
| 组分&重悬 | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| 纯化 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Uniprot ID | P11308 |
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文献和实验T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers
Immunohistochemistry using Anti-Ganglioside Antibodies
supernatant containing antiganglioside mAb overnight at 4°C. The time of incubation may range from 30 min. to overnight as determined by experience. 5. Wash with 1% BSA in PBS 4 times. 6. Incubate in FITC-conjugated goat anti-mouse IgM F(ab
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