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- DIMA
- DME904244
- 2025年07月14日
- Mouse
- Human
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- 亚型：
IgG2b
- 形态：
请咨询
- 保存条件：
Store at -20°C
- 标记物：
Unconjugated
- 适应物种：
Human
- 保质期：
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- 级别：
仅用于科研
- 库存：
1 week
- 宿主：
Mouse
- 浓度：
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- 靶点：
Asialoglycoprotein Receptor 2
- 规格：
100ul
| 背景 | This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
|---|---|
| 别名 | ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2 |
| 推荐稀释比 | WB 1:4000, IF 1:100 |
| 组分&重悬 | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| 纯化 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Uniprot ID | P07307 |
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文献和实验Therapeutic Human Monoclonal Antibodies in Inflammatory Diseases
almost any cell surface or secreted molecule with remarkable efficacy and safety. In this chapter, the application of human mAbs in the treatment of inflammatory diseases is reviewed. We discuss in detail several mAb-based drugs such as anti-tumor necrosis factor
spreading, we developed a method engaging integrin signaling by use of an immobilized anti-integrin monoclonal antibody (mab) directed against the fibronectin (FN) receptor integrin α5β1. ECV 304 cells were plated onto FN or immobilized mab JBS5 (anti
医学生理病理与临床分册2000，20（2）：137-140.[5]Yang XD，Jia XC，Corvalan JR， etal.Development of ABX-EGF，a fully human anti-EGF receptor monoclonal antibody，forcancertherapy.Hematology， 2001，38：17-13．[6]Herbst RS，langer CJ.Epidermal growth factor receptors as a target
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