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Anti-ERCC1 OTI1C3;Mouse mAb

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  • 询价
  • DIMA
  • DME901426
  • 2025年07月13日
  • Mouse
  • Human, Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 亚型

      IgG1

    • 形态

      请咨询

    • 保存条件

      Store at -20°C

    • 标记物

      Unconjugated

    • 适应物种

      Human, Mouse

    • 保质期

      请咨询

    • 级别

      仅用于科研

    • 库存

      1 week

    • 宿主

      Mouse

    • 浓度

      请咨询

    • 靶点

      ERCC1

    • 规格

      100ul

    背景 The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq]
    别名 COFS4; RAD10; UV20
    推荐稀释比 WB 1:2000, FLOW 1:100
    组分&重悬 PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
    纯化 Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
    Uniprot ID P07992

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    图标文献和实验
    相关实验
    • T-Cell Activation Using mAb to CD3

      splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16

    • Purification of mAb (IgG)

        Purification of mAb (IgG) by Chang-Duk Jun, 03/14/2000 Purpose Materials Antibody 7E3 , 2L sup grown in flasks, frozen and thawed overnight. BioRad Affi-Gel Protein A MAPS II Buffers

    • Immunohistochemistry using Anti-Ganglioside Antibodies

      supernatant containing antiganglioside mAb overnight at 4°C. The time of incubation may range from 30 min. to overnight as determined by experience. 5. Wash with 1% BSA in PBS 4 times. 6. Incubate in FITC-conjugated goat anti-mouse IgM F(ab

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    Anti-ERCC1 OTI1C3;Mouse mAb
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