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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -80°C after receiving vials.
- 库存:
4-5 weeks
- 规格:
20 ug
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文献和实验Functional Analysis of Mutant Mitochondrial DNA Polymerase Proteins Involved in Human Disease
to disease. Furthermore, crucial knowledge concerning the role of pol γ in mtDNA replication and repair can be acquired. Here we present the protocols to characterize mutant DNA pol γ proteins, namely, assays for processive DNA synthesis, exonuclease activity
DamIP: Using Mutant DNA Adenine Methyltransferase to Study DNA‐Protein Interactions In Vivo
for studying DNA?protein interaction in vivo. A mutant form of DNA adenine methyltransferase (DamK9A) from E. coli is fused to the protein of interest and expressed. The fusion protein will bind to target binding sites and introduce N 6 ?adenine methylation
Clearance of Mutant Aggregate-Prone Proteins by Autophagy
The accumulation of mutant aggregate-prone proteins is a feature of several human disorders, collectively referred to as protein conformation disorders or proteinopathies. We have shown that autophagy, a cytosolic, non-specific bulk
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