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- PME46180
- 2025年07月11日
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- 保存条件：
-80°C
- 保质期：
请咨询
- 英文名：
Mouse Tgfb1 (NM_011577) Protein
- 库存：
1 week
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
20 ug
| 产品类别 | ECD Proteins |
|---|---|
| 靶点 | Tgfb1 |
| Uniprot ID | P04202 |
| 背景 | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer. [provided by RefSeq, Aug 2016] |
| 描述 | Purified recombinant protein of Mouse transforming growth factor, beta 1 (Tgfb1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug |
| 分子量 | 44.8 kDa |
| 纯度 | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| 别名 | TGF-beta; TGF-beta1; Tgfb; Tgfb-1; TGFbeta; TGFbeta1 |
| 标签 | C-MYC/DDK |
| 表达宿主 | HEK293T |
| 组分与重悬 | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
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