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- PME32211
- 2025年07月11日
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- 保存条件：
-80°C
- 保质期：
请咨询
- 英文名：
Human Angiotensinogen (AGT) (NM_000029) Protein
- 库存：
1 week
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
20 ug
| 产品类别 | ECD Proteins |
|---|---|
| 靶点 | Angiotensinogen |
| Uniprot ID | P01019 |
| 背景 | The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Nov 2019] |
| 描述 | Recombinant protein of human angiotensinogen (serpin peptidase inhibitor, clade A, member 8) (AGT) |
| 分子量 | 49.7 kDa |
| 纯度 | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| 别名 | ANHU; hFLT1; SERPINA8 |
| 标签 | C-Myc/DDK |
| 表达宿主 | HEK293T |
| 组分与重悬 | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
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