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文献和实验Neuropathological Diagnosis of Human Prion Disease: PrP Immunocytochemical Techniques
in tissue sections. Since it is now known that CJD and related diseases are associated with accumulation in the brain of a protease-resistant protein known as prion protein (4 ), the demonstration of prion presence in suspected cases would represent
nm23 Protein Expression by Western Blotting in Patients with Epithelial Ovarian Carcinoma
and discriminate the two isoforms of nm23, H1, and H2 (1, 2). nm23-H1 is about 18.5 kD (3 ) and nm23-H2 is 17 kD (4 ), hence, they migrate as two distinct bands on a standard SDS polyacrylamide gel. Because the two isoforms are very highly conserved
Secondary structure of prion mRNA
of structural elements in mRNA of prion protein From the EMBL data bank, 23 PrP mRNA sequences of the following species were available: three rodents (mouse, hamster, rat), two ruminants (cattle, sheep), the human and 17 non-human primates consisting
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