Biotinylated Anti-Human Amphir

Biotinylated Anti-Human Amphiregulin

Amphiregulin is an EGF-related growth factor that signals through the EGF/TGF-α receptor,and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin’s extracellular domain is proteolytically processed to release the mature protein.There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity.