Rabbit polyclonal BAX Antibody

gene_symbol：BAX
predicted_size：21 kDa
Uniprot ID：Q7812
description：Rabbit polyclonal BAX Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
immunogen：Synthetic peptide conjugated to KLH derived from within residues 100-170 of Human BAX.
recommended_dilution：WB 1:2000, IHC 1:150
predicted_size：21 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Rabbit
applications：IHC, WB
reactivities：Human, Mouse, Rat