ITGAM mouse monoclonal antibod

gene_symbol：ITGAM
predicted_size：125.4 kDa
Uniprot ID：P11215
description：ITGAM mouse monoclonal antibody, clone OTI2D11 (formerly 2D11)
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
immunogen：Full length human recombinant protein of human ITGAM (NP_000623) produced in HEK293T cell.
recommended_dilution：WB 1:500, IHC 1:150
predicted_size：125.4 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：IHC, WB
reactivities：Human