DCX mouse monoclonal antibody,

gene_symbol：DCX
predicted_size：40.4 kDa
Uniprot ID：O4362
description：DCX mouse monoclonal antibody, clone OTI4A3 (formerly 4A3)
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
immunogen：Full length human recombinant protein of human DCX (NP_835365) produced in HEK293T cell.
recommended_dilution：WB 1:2000, IF 1:100, FLOW 1:100
predicted_size：40.4 kDa
buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
host_species：Mouse
applications：FC, IF, WB
reactivities：Human, Mouse, Rat