Anti-NFASC Rabbit Polyclonal A

gene_symbol：NFASC
predicted_size：null
Uniprot ID：O94856
description：Anti-NFASC Rabbit Polyclonal Antibody
clonality：Polyclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth; neurite fasciculation; and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein; gliomedin; ankyrin 3 (ankyrin-G); and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing; and the full-length nature of some variants has not been determined.
immunogen：Synthetic peptide corresponding to a region derived from 1225-1240 amino acids of human neurofascin
recommended_dilution：IHC: 20-100 Positive control: Human tonsil Predicted cell location: Cell membrane
predicted_size：null
buffer：PBS pH7.3, 0.05% NaN3, 50% glycerol
host_species：Rabbit
applications：IHC
reactivities：Human, Mouse, Rat