OriGene Histone H2A.X (H2AFX)

ProductName：Histone H2A.X (H2AFX) Rabbit Monoclonal Antibody [Clone ID: OTIR1C4]
description：H2AX Rabbit monoclonal antibody,clone OTIR1C4
symbol：Histone H2A.X
synonyms：H2A.X; H2A/X; H2AFX
locusid：3014
Concentration：1 mg/ml
sub_category：Primary Antibodies
uniprot_id：P16104
Applications：WB
CNdelivery：2周
RecommendDilution：WB 1:500-1:2000
Reactivity：Human, Mouse
Immunogen：Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human H2AX (NP_002096). The exact sequence is proprietary.
Purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation：Unconjugated
ProteinFamilies：Druggable Genome
ProteinPathways：Systemic lupus erythematosus
GeneName：H2A.X variant histone
Background：Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
Buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter：IgG
predicted_size：15.1 kDa