OriGene BRG1 (SMARCA4) Rabbit

ProductName：BRG1 (SMARCA4) Rabbit Monoclonal Antibody [Clone ID: OTIR4D3]
description：Brg1 Rabbit monoclonal antibody,clone OTIR4D3
symbol：BRG1
synonyms：BAF190; BAF190A; BRG1; CSS4; hSNF2b; MRD16; RTPS2; SNF2; SNF2-beta; SNF2L4; SNF2LB; SWI2
locusid：6597
Concentration：1.00mg/ml
sub_category：Primary Antibodies
uniprot_id：P51532
Applications：IHC
CNdelivery：2周
RecommendDilution：IHC 1:600
Reactivity：Human
Immunogen：Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Brg1 (NP_001122321). The exact sequence is proprietary.
Purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation：Unconjugated
ProteinFamilies：Druggable Genome, Transcription Factors
ProteinPathways：null
GeneName：SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Background：The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter：IgG
predicted_size：188 kDa