OriGene TdT (DNTT) Rabbit Mono

ProductName：TdT (DNTT) Rabbit Monoclonal Antibody [Clone ID: OTIR1E10]
description：TDT Rabbit monoclonal antibody,clone OTIR1E10
symbol：TdT
synonyms：TDT
locusid：1791
Concentration：1.00mg/ml
sub_category：Primary Antibodies
uniprot_id：P04053
Applications：IHC
CNdelivery：2周
RecommendDilution：IHC 1:2000
Reactivity：Human
Immunogen：Human recombinant protein fragment corresponding to the N-terminus of human TDT (NP_001017520) produced in E.coli.
Purification：Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：Hematopoietic cell lineage, Non-homologous end-joining
GeneName：DNA nucleotidylexotransferase
Background：This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
Buffer：PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
isotypes_filter：IgG
predicted_size：58.4 kDa