OriGene IKK alpha (CHUK) Rabbi

ProductName：IKK alpha (CHUK) Rabbit Monoclonal Antibody
description：IKK alpha Antibody
symbol：CHUK
synonyms：CHUK; I-kappa-B kinase-alpha; I-kappa-B kinase 1; I-kappa-B kinase alpha; IkappaB kinase; IkBKA; IkB kinase alpha subunit; IKK-A; IKK-a kinase; IKK-alpha; IKK1; IKKA
locusid：1147
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：O15111
Applications：FC, ICC/IF, IHC, IP, WB
CNdelivery：2周
RecommendDilution：WB 1:5000~1:20000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Reactivity：Human, Mouse, Rat
Immunogen：A synthesized peptide derived from human IKK alpha
Purification：Affinity-chromatography
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：conserved helix-loop-helix ubiquitous kinase
Background：Plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKβ (Ser176 and Ser180 in IKKα), which causes conformational changes, resulting in kinase activation.
Buffer：Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
isotypes_filter：IgG
predicted_size：85kDa