OriGene IKB alpha (NFKBIA) Rab

ProductName：IKB alpha (NFKBIA) Rabbit Monoclonal Antibody [Clone ID: R08-2D9]
description：Phospho-IKB alpha (Ser32) Rabbit monoclonal Antibody
symbol：NFKBIA
synonyms：I-kappa-B-alpha; IkappaBalpha; IkB-alpha; IKBA; MAD-3; MAD3; NFKBI
locusid：4792
Concentration：lot specific
sub_category：Primary Antibodies
uniprot_id：P25963
Applications：IP, WB
CNdelivery：2周
RecommendDilution：WB: 1/1000
IP: 1/20
Reactivity：Human, Mouse
Immunogen：A synthetic phosphopeptide corresponding to residues surrounding Ser32 of human IKB alpha (Phosphorylated)
Purification：Affinity Purified
Conjugation：Unconjugated
ProteinFamilies：null
ProteinPathways：null
GeneName：NFKB inhibitor alpha
Background：Swiss-Prot Acc.P25963.Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Buffer：50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
isotypes_filter：IgG
predicted_size：Calculated MW: 36 kDa; Observed MW: 36 kDa