Recombinant FGF-22 (Fibroblast

gene_symbol
Description：Recombinant FGF-22 (Fibroblast growth factor-22)，Human
Accn
Unipro ID：Q9HCT0
Synonyms：UNQ2500/PRO5800
Species：Human
Amount：20 ug
Delivery time：2周
Expression sequence：TPSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS with polyhistidine tag and SUMO tag at the N-terminus.
Tags：His-SUMO Tag (N-term)
PredictedMW：The protein has a calculated MW of 29.35 kDa. The protein migrates as 36 kDa under reducing condition (SDS-PAGE analysis).
Buffer：The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.
Stability
Bioactivity：Measure by its ability to induce 3T3 cells proliferation. The ED₅₀ for this effect is <2 ng/mL.
Purity：>98% as determined by SDS-PAGE.
Concentration
Preparation
Endotoxin：<0.1 EU per 1 μg of the protein by the LAL method.
Shipping
Background：Fibroblast Growth Factors-22 (FGF-22) is a 22.3 kDa member of the fibroblast Growth Factors with 209 amino acid residues. FGF-22 is expressed from brain, skin, horizontal cells, bipolar cells, rod photoreceptor cells, muller glia cells. Involving fasting response, glucose homeostasis, lipolysis, lipogenesis and hair development.