Purified recombinant protein o

gene_symbol：PGC1 alpha
Description：Purified recombinant protein of Human peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PPARGC1A), Phe511-End, with N-terminal His tag, expressed in E.coli, 50ug
Accn：NM_013261
Unipro ID：Q9UBK2
Synonyms：LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1
Species：Human
Amount：50 ug
Delivery time：现货
Expression sequence：A DNA sequence encoding the region(Phe511-End) of PPARGC1A
Tags：N-His
PredictedMW：34.6 kDa
Buffer：50 mM Tris-HCl, pH 8.0, 8 M urea
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]