Collagen type I human protein,

gene_symbol：COL1A1
Description：Collagen type I human protein, 0.5 mg
Accn：NM_000088
Unipro ID
Synonyms：COL1A1, COL1A2, Alpha-1 type I collagen, Alpha-2 type I collagen
Species：Human
Amount：500 ug
Delivery time：7周
Expression sequence
Tags
PredictedMW
Buffer：State: Liquid (sterile filtered) purified Ig fraction.Buffer System: 0.5M Acetic AcidPreservative: 0.01% (w/v) Sodium AzideStabilizer: None
Stability：Shelf life: 6 months from despatch.
Bioactivity
Purity：>98% (Chromatographically and Immunologically pure).
Concentration：lot specific
Preparation：Liquid (sterile filtered) purified Ig fraction.
Endotoxin
Shipping
Background：This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]