Purified recombinant protein o

gene_symbol：Caspase 9
Description：Purified recombinant protein of Human caspase 9, apoptosis-related cysteine peptidase (CASP9), transcript variant alpha, full length, with N-terminal HIS tag, expressed in E. coli, 50ug
Accn：NM_001229
Unipro ID：P55211
Synonyms：APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56
Species：Human
Amount：50 ug
Delivery time：现货
Expression sequence：A DNA sequence encoding human full-length CASP9
Tags：N-His
PredictedMW：46.1 kDa
Buffer：50 mM Tris-HCl, pH 8.0, 8 M urea
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]