Purified recombinant protein o

gene_symbol：PFKFB1
Description：Purified recombinant protein of Human 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Accn：NM_002625
Unipro ID：P16118
Synonyms：F6PK; HL2K; PFRX
Species：Human
Amount：50 ug
Delivery time：现货
Expression sequence：A DNA sequence encoding human full-length PFKFB1
Tags：N-His
PredictedMW：54.5 kDa
Buffer：25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]