Recombinant protein of human g

gene_symbol：GFI1
Description：Recombinant protein of human growth factor independent 1 transcription repressor (GFI1), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Accn：NM_005263
Unipro ID：Q99684
Synonyms：GFI-1; GFI1A; SCN2; ZNF163
Species：Human
Amount：50 ug
Delivery time：2周
Expression sequence：A DNA sequence encoding human full-length GFI1
Tags：N-His
PredictedMW：45.3 kDa
Buffer：25 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1% sarkosyl, 10% glycerol
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]