Recombinant protein of human P

gene_symbol：TMS1
Description：Recombinant protein of human PYD and CARD domain containing (PYCARD), transcript variant 2, 20 µg
Accn：NM_145182
Unipro ID：Q9ULZ3
Synonyms：ASC; CARD5; TMS; TMS-1; TMS1
Species：Human
Amount：20 ug
Delivery time：现货
Expression sequence：Recombinant protein was produced with TrueORF clone, [RC224051]. Click on the TrueORF clone link to view cDNA and protein sequences.
Tags：C-Myc/DDK
PredictedMW：19.8 kDa
Buffer：25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation：Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Endotoxin
Shipping
Background：This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]