Purified recombinant protein of Homo sapiens myelin basic protein (MBP), transcript variant 7, 20 µg

Purified recombinant protein o

f Homo sapiens myelin basic protein (MBP), transcript variant 7, 20 µg
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  • TP321469
  • 2025年10月18日
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    gene_symbol:Myelin Basic Protein
    Description:Purified recombinant protein of Homo sapiens myelin basic protein (MBP), transcript variant 7, 20 µg
    Accn:NM_001025101
    Unipro ID:P02686
    Synonyms
    Species:Human
    Amount:20 ug
    Delivery time:4周
    Expression sequence:>RC221469 representing NM_001025101 Red=Cloning site Green=Tags(s) MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQDTAVTDSKRT ADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRP SQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKDSHHPARTAHYGSLPQKS HGRTQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQRPGFGYGGRASDYKSAHKGFKGVDA QGTLSKIFKLGGRDSRSGSPMARR TRTRPLEQKLISEEDLAANDILDYKDDDDKV
    Tags:C-Myc/DDK
    PredictedMW:32.9 kDa
    Buffer:25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
    Stability:Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
    Bioactivity
    Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
    Concentration:>0.05 µg/µL as determined by microplate BCA method
    Preparation:Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
    Endotoxin
    Shipping
    Background:The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]

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