Purified recombinant protein o
f human lymphocyte-activation gene 3 (LAG3), with C-terminal DDK/His tag, expressed in human cells, 20 µg- ￥6650
- OriGene
- TP700220
- 2025年10月16日
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Description：Purified recombinant protein of human lymphocyte-activation gene 3 (LAG3), with C-terminal DDK/His tag, expressed in human cells, 20 µg
Accn：NM_002286
Unipro ID：P18627
Synonyms：CD223
Species：Human
Amount：20 ug
Delivery time：4周
Expression sequence：A DNA sequence from TrueORF clone, [RC220269], encoding the region (Val29-Leu450) of human LAG3
Tags：C-DDK/His
PredictedMW：48 kDa
Buffer：PBS, pH 7.4, 10% glycerol
Stability：Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Bioactivity
Purity：> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration：>0.05 µg/µL as determined by microplate BCA method
Preparation
Endotoxin
Shipping
Background：Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]
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文献和实验Introduction of human 14-3-3 proteins
acid sequence of human 14-3-3 protein eta was highly homologous to that of previously reported bovine and rat 14-3-3 proteins with only two amino acid differences.The sequence carries structural features as putative regions responsible for activation
that encodes a hybrid transcription factor (Fig. 1A). The hybrid transcription factor consists of two domains: a DNA-binding domain and a transcriptional activation domain. We used the Gal4 transcriptional activation domain fused to the Zif268 protein
Scintillation Proximity Assay (SPA) Technology to Study Biomolecular Interactions
screening technology. Drug Discovery Today. 1:287‐294. Cowell, I.G. 1994. Repression versus activation in the control of gene transcription. Trends Biochem. Sci. 19:38‐42
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